Doxylamine
- Generic Name
- Doxylamine
- Brand Names
- Bonjesta, Dalmacol, Dayquil Sinex, Diclectin, Diclegis, Mersyndol, Nyquil Cough, Poly Hist Forte Reformulated Nov 2013, Robafen DM, Robitussin Nighttime Cough DM, Safetussin PM, Unisom, Wal-som (doxylamine)
- Drug Type
- Small Molecule
- Chemical Formula
- C17H22N2O
- CAS Number
- 469-21-6
- Unique Ingredient Identifier
- 95QB77JKPL
Overview
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Background
Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Indication
用于枯草热、过敏性鼻炎，短期用于失眠。
Associated Conditions
- Common Cold
- Insomnia
- Mild Allergic Rhinitis
- Nausea
- Symptoms Flu
- Vomiting
Clinical Trials
FDA Approved Products
DICLEGIS
Manufacturer:Duchesnay USA, Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2017/01/31
NDC:55494-100
Doxylamine Succinate and Pyridoxine Hydrochloride
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:10 mg in 1 1
Approved: 2020/10/14
NDC:72162-1485
Doxylamine Succinate and Pyridoxine Hydrochloride
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:10 mg in 1 1
Approved: 2020/10/14
NDC:63629-2184
Doxylamine Succinate and Pyridoxine Hydrochloride
Manufacturer:Par Pharmaceutical, Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2020/10/14
NDC:49884-186
Doxylamine succinate and Pyridoxine hydrochloride
Manufacturer:Bionpharma Inc.,
Route:ORAL
Strength:10 mg in 1 1
Approved: 2023/12/11
NDC:69452-206
Singapore Approved Products
DICLECTIN DELAYED RELEASE TABLETS 10MG/10MG
Manufacturer:Duchesnay Inc.
Form:TABLET, DELAYED RELEASE
Strength:10mg
Online:Yes
Approved: 2017/07/20
Approval:SIN15301P
BONJESTA EXTENDED-RELEASE TABLETS 20 MG/20 MG
Manufacturer:Duchesnay Inc.
Form:TABLET, FILM COATED, EXTENDED RELEASE
Strength:20.0mg
Online:Yes
Approved: 2023/09/18
Approval:SIN16865P
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