MedPath

Triptolide

Generic Name
Triptolide
Drug Type
Small Molecule
Chemical Formula
C20H24O6
CAS Number
38748-32-2
Unique Ingredient Identifier
19ALD1S53J
Background

Triptolide has been used in trials studying the treatment of HIV, Crohn's Disease, Intestinal Diseases, Gastrointestinal Diseases, and Digestive System Diseases, among others.

Indication

用于治疗银屑病(牛皮癣)。

Minnelide and Osimertinib for the Treatment of Advanced EGFR Mutated Non-Small Cell Lung Cancer

Phase 1
Recruiting
Conditions
Stage III Lung Cancer AJCC v8
Unresectable Lung Non-Small Cell Carcinoma
Advanced Lung Non-Small Cell Carcinoma
Stage IVB Lung Cancer AJCC v8
Stage IIIB Lung Cancer AJCC v8
Stage IIIC Lung Cancer AJCC v8
Stage IVA Lung Cancer AJCC v8
Locally Advanced Lung Non-Small Cell Carcinoma
Stage IIIA Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Interventions
First Posted Date
2021-12-22
Last Posted Date
2025-02-24
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
30
Registration Number
NCT05166616
Locations
🇺🇸

City of Hope Medical Center, Duarte, California, United States

Safety and Efficacy of Triptolide Wilfordii in New Onset HIV-1 Infection

Phase 3
Completed
Conditions
HIV-infection/AIDS
Interventions
Drug: Placebo Oral Tablet
First Posted Date
2018-01-18
Last Posted Date
2022-04-08
Lead Sponsor
Peking Union Medical College Hospital
Target Recruit Count
353
Registration Number
NCT03403569
Locations
🇨🇳

The Eighth People's Hospital of Guangzhou, Guangzhou, Guangdong, China

🇨🇳

The Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China

🇨🇳

Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou, Fujian, China

and more 4 locations

Impact on T Cell Immune Activation and Inflammation of Triptolide Woldifii in HIV-infected Immunological Non-responders

Phase 1
Conditions
HIV
Interventions
Drug: cART
Drug: placebo
First Posted Date
2013-03-25
Last Posted Date
2013-03-25
Lead Sponsor
LI Taisheng
Target Recruit Count
150
Registration Number
NCT01817283
Locations
🇨🇳

Peking Union Medical College Hospital, Beijing, China

© Copyright 2025. All Rights Reserved by MedPath