Mesalazine

Generic Name
Mesalazine
Brand Names
Apriso, Asacol, Canasa, Delzicol, Lialda, Mezavant, Pentasa, Rowasa, Salofalk, Zaldyon
Drug Type
Small Molecule
Chemical Formula
C7H7NO3
CAS Number
89-57-6
Unique Ingredient Identifier
4Q81I59GXC
Background

An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease . Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stabil...

Indication

适用于溃疡性结肠炎和克罗恩病(Crohn病)。

Associated Conditions
Acute Ulcerative Colitis, Crohn's Disease Relapse, Crohn's Ileocolitis, Mild to Moderate Ulcerative Colitis, Proctitis, Proctitis, Ulcerative, Proctosigmoiditis, Ulcerative Colitis in Remission, Mild Ulcerative Colitis, Mild to moderate distal ulcerative colitis, Moderate Ulcerative colitis
Associated Therapies
-

Efficacy and Safety of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-09-09
Last Posted Date
2021-06-14
Lead Sponsor
Shire
Target Recruit Count
829
Registration Number
NCT00151892
Locations
🇨🇱

Hospital San Juan de Dios, Santiago, Chile

🇮🇳

Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India

🇲🇽

Instituto Nacional de Ciencias médicas y Nutrición Salvador Zubirán, Mexico DF, Mexico

and more 137 locations

Effect of an Anti-Inflammatory Drug on Gut Mucosa in HIV Infected Patients

Phase 1
Completed
Conditions
First Posted Date
2003-09-30
Last Posted Date
2007-05-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
14
Registration Number
NCT00069498
Locations
🇺🇸

David Geffen School of Medicine at UCLA, Los Angeles, California, United States

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