Etoricoxib
- Generic Name
- Etoricoxib
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C18H15ClN2O2S
- CAS Number
- 202409-33-4
- Unique Ingredient Identifier
- WRX4NFY03R
- Background
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid. It is approved in more than 60 countries worldwide but not in the US.
- Indication
For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.
- Associated Conditions
- Ankylosing Spondylitis (AS), Gout, Osteoarthritis (OA), Rheumatoid Arthritis, Moderate Pain
- Associated Therapies
- -
The Effect of Anti-inflammatory Analgesics on Pain Following Hallux Valgus Surgery
- First Posted Date
- 2008-08-13
- Last Posted Date
- 2010-01-20
- Lead Sponsor
- Karolinska Institutet
- Target Recruit Count
- 100
- Registration Number
- NCT00733421
- Locations
- 🇸🇪
Foot & Ancle Surgical Center, Stockholm, Sweden
Etoricoxib With Flavoxate for Reducing Morphine Requirement After Transurethral Prostatectomy (TURP)
- Conditions
- Pain
- Interventions
- First Posted Date
- 2007-02-27
- Last Posted Date
- 2009-02-05
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 128
- Registration Number
- NCT00440739
- Locations
- 🇹🇭
Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Combined Antiinflammatory and Angiostatic Therapy in Patients With Hormone-refractory Prostate Cancer
- Conditions
- Prostate Cancer
- Interventions
- First Posted Date
- 2007-01-29
- Last Posted Date
- 2016-11-21
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 67
- Registration Number
- NCT00427999
- Locations
- 🇩🇪
Novartis Investigative Site, Tübingen, Germany
Etoricoxib for Routine Post-operative Pain Prophylaxis in Laparoscopic Surgery
- Conditions
- HysterectomyTubal ExcisionOvariectomyPostoperative Pain
- First Posted Date
- 2006-09-08
- Last Posted Date
- 2011-07-01
- Lead Sponsor
- Ullevaal University Hospital
- Target Recruit Count
- 126
- Registration Number
- NCT00373464
- Locations
- 🇳🇴
Ullevaal University Hospital, Oslo, Norway
Rheumatoid Arthritis Dose Ranging Study (0663-086)(COMPLETED)
- First Posted Date
- 2005-12-12
- Last Posted Date
- 2022-02-09
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 761
- Registration Number
- NCT00264147
Drug Development Updates
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