MedPath

Etoricoxib

Generic Name
Etoricoxib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H15ClN2O2S
CAS Number
202409-33-4
Unique Ingredient Identifier
WRX4NFY03R
Background

Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid. It is approved in more than 60 countries worldwide but not in the US.

Indication

For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout.

Associated Conditions
Ankylosing Spondylitis (AS), Gout, Osteoarthritis (OA), Rheumatoid Arthritis, Moderate Pain
Associated Therapies
-
Clinical Trials
Related News

Immediate Analgesic Effects of Cheek Acupuncture for Acute Gouty Arthritis

Not Applicable
Completed
Conditions
Acupuncture
Acute Pain
Acute Gout Arthritis
Interventions
Other: cheek acupuncture
Drug: Etoricoxib
First Posted Date
2023-08-21
Last Posted Date
2024-07-18
Lead Sponsor
Guangdong Provincial Hospital of Traditional Chinese Medicine
Target Recruit Count
76
Registration Number
NCT06001112
Locations
🇨🇳

Yupinglin Lin, GuangZhou, Guangdong, China

Prevention of Taxane-associated Acute Pain Syndrome With Etoricoxib

Phase 2
Completed
Conditions
Pain Syndrome
Interventions
Drug: Etoricoxib
First Posted Date
2020-09-25
Last Posted Date
2022-02-14
Lead Sponsor
Guangdong Provincial People's Hospital
Target Recruit Count
144
Registration Number
NCT04565600
Locations
🇨🇳

Guangdong General Hospital, Guangzhou, Guangdong, China

Oral Huzhang Granules for Acute Gouty Arthritis

Phase 2
Conditions
Gouty Arthritis
Interventions
Drug: Huzhang granule
Drug: Etoricoxib
Drug: Etoricoxib Placebo
Drug: Huzhang granule Placebo
First Posted Date
2020-07-08
Last Posted Date
2020-07-08
Lead Sponsor
Shanghai Yueyang Integrated Medicine Hospital
Target Recruit Count
267
Registration Number
NCT04462666

Etoricoxib vs Aceclofenac in the Treatment of Patients With Rheumatoid Arthritis

Phase 4
Completed
Conditions
Rheumatoid Arthritis
Interventions
Drug: Aceclofenac
Drug: Etoricoxib
First Posted Date
2019-10-30
Last Posted Date
2019-10-30
Lead Sponsor
Chung Shan Medical University
Target Recruit Count
40
Registration Number
NCT04144101

Rebound Pain After Operations for Distal Radius Fractures With a Volar Plate in Brachial Plexus Block

Phase 3
Completed
Conditions
Brachial Plexus Block
Pain, Postoperative
Interventions
Drug: NaCl (Control)
Drug: Dexamethasone
Drug: Paracetamol
Drug: EtoriCoxib
Drug: Oxycodone
Drug: Ropivacaine
First Posted Date
2017-01-05
Last Posted Date
2020-09-21
Lead Sponsor
Oslo University Hospital
Target Recruit Count
53
Registration Number
NCT03011905
Locations
🇳🇴

Oslo Universitetssykehus, Ullevaal, dept of anaesthesiology, legevakten, Oslo, Norway

Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty

Phase 3
Completed
Conditions
Pain, Postoperative
Interventions
Drug: Placebo
Drug: pregabalin
Drug: Etoricoxib
Drug: paracetamol
Drug: Morphine
Drug: Ropivacaine
First Posted Date
2016-11-03
Last Posted Date
2017-09-14
Lead Sponsor
National University Hospital, Singapore
Target Recruit Count
116
Registration Number
NCT02954484

Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific Inhibitor

Not Applicable
Completed
Conditions
Adverse Anesthesia Outcome
Interventions
Drug: Placebo
Drug: Etoricoxib
First Posted Date
2016-08-31
Last Posted Date
2016-08-31
Lead Sponsor
Bnai Zion Medical Center
Target Recruit Count
60
Registration Number
NCT02884986
Locations
🇮🇱

Bnai Zion Medical Center, Haifa, Israel

Lornoxicam Versus Etoricoxib in Postoperative Pain After Total Knee Arthroplasty

Phase 3
Completed
Conditions
Postoperative Pain
Interventions
Drug: Lornoxicam
Drug: Etoricoxib
First Posted Date
2016-04-26
Last Posted Date
2016-04-26
Lead Sponsor
Foisor Orthopedics Clinical Hospital
Target Recruit Count
120
Registration Number
NCT02750917

Dexketoprofen and Etoricoxib in Patients Undergoing Hip Arthroplasty

Phase 4
Completed
Conditions
Pain, Postoperative
Interventions
Drug: Dexketoprofen
Drug: Etoricoxib
First Posted Date
2015-10-06
Last Posted Date
2016-05-03
Lead Sponsor
Kuopio University Hospital
Target Recruit Count
24
Registration Number
NCT02568735

Analgesic Benefit of Preoperative vs. Postoperative Etoricoxib in Total Knee Arthroplasty

Not Applicable
Completed
Conditions
Postoperative Pain
Interventions
Drug: Etoricoxib
Drug: Placebo
First Posted Date
2015-08-27
Last Posted Date
2015-08-27
Lead Sponsor
Foisor Orthopedics Clinical Hospital
Target Recruit Count
165
Registration Number
NCT02534610
Locations
🇷🇴

Foisor Orthopedics Clinical Hospital, Bucharest, Romania

© Copyright 2025. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy