Pomalidomide

Generic Name
Pomalidomide
Brand Names
Imnovid, Pomalyst, Imnovid (previously Pomalidomide Celgene), Pomalidomide Viatris, Pomalidomide Zentiva, Pomalidomide Krka, Pomalidomide Accord
Drug Type
Small Molecule
Chemical Formula
C13H11N3O4
CAS Number
19171-19-8
Unique Ingredient Identifier
D2UX06XLB5
Background

Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.

Indication

Pomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and have demonstrated disease progression on or within 60 days of completion of the last therapy. It is also indicated for the treatment of Kaposi's sarcoma (KS) in AIDS patients who have failed highly active antiretroviral thera...

Associated Conditions
Kaposi's Sarcoma, Multiple Myeloma (MM)
Associated Therapies
-

CC-4047 With Gemcitabine for Untreated Advanced Carcinoma of the Pancreas

Phase 1
Completed
Conditions
Interventions
First Posted Date
2007-10-08
Last Posted Date
2013-03-13
Lead Sponsor
SCRI Development Innovations, LLC
Target Recruit Count
23
Registration Number
NCT00540579
Locations
🇺🇸

University of Colorado Cancer Center, Aurora, Colorado, United States

🇺🇸

Tennessee Oncology, PLLC, Nashville, Tennessee, United States

A Phase I/II Study to Determine the Maximum Tolerated Dose (MTD) and Safety of CC-4047 (Pomalidomide) Administered in Conjunction With Cisplatin and Etoposide

First Posted Date
2007-10-01
Last Posted Date
2019-11-19
Lead Sponsor
Celgene
Target Recruit Count
22
Registration Number
NCT00537511
Locations
🇺🇸

Pennsylvania State University, Hershey, Pennsylvania, United States

🇺🇸

Ireland Cancer Center, Case Western Reserve University, Division of Hematology/Oncology, Cleveland, Ohio, United States

🇺🇸

University of Texas Southwestern Medical Center, Dallas, Texas, United States

and more 3 locations

A Phase II Study of Pomalidomide in Myelofibrosis With Myeloid Metaplasia

First Posted Date
2007-04-20
Last Posted Date
2019-11-20
Lead Sponsor
Celgene
Target Recruit Count
88
Registration Number
NCT00463385
Locations
🇦🇹

Medical University of Vienna, Department of Internal Medicine, Hematology, Vienna, Austria

🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

🇺🇸

New York Presbyterian HospitalWeill Medical College of Cornell University, New York, New York, United States

and more 8 locations
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