Curcumin

Generic Name
Curcumin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H20O6
CAS Number
458-37-7
Unique Ingredient Identifier
IT942ZTH98
Background

Curcumin, also known as diferuloylmethane, is an active component in the golden spice turmeric (Curcuma longa) and in Curcuma xanthorrhiza oil. It is a highly pleiotropic molecule that exhibits antibacterial, anti-inflammatory, hypoglycemic, antioxidant, wound-healing, and antimicrobial activities . Due to these properties, curcumin has been investigated for...

Indication

No approved therapeutic indications.

Associated Conditions
-
Associated Therapies
-
Clinical Trials
Related News

Curcumin in Treating Patients With Familial Adenomatous Polyposis

First Posted Date
2008-03-24
Last Posted Date
2017-09-29
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
44
Registration Number
NCT00641147
Locations
🇵🇷

University of Puerto Rico, San Juan, Puerto Rico

🇺🇸

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States

A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)

Phase 3
Completed
Conditions
Optic Atrophy, Hereditary, Leber
Interventions
Drug: curcumin
First Posted Date
2007-09-12
Last Posted Date
2012-12-24
Lead Sponsor
Mahidol University
Target Recruit Count
70
Registration Number
NCT00528151
Locations
🇹🇭

Professor Wanicha Chuenkongkaew, Bangkok, Thailand

Phase III Trial of Gemcitabine, Curcumin and Celebrex in Patients With Advance or Inoperable Pancreatic Cancer

Phase 3
Conditions
Pancreatic Cancer
First Posted Date
2007-06-14
Last Posted Date
2007-06-14
Lead Sponsor
Tel-Aviv Sourasky Medical Center
Registration Number
NCT00486460
Locations
🇮🇱

Sourasky Medical Center, Tel Aviv, Israel

Phase II A Trial of Curcumin Among Patients With Prevalent Subclinical Neoplastic Lesions (Aberrant Crypt Foci)

First Posted Date
2006-08-17
Last Posted Date
2015-08-27
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
44
Registration Number
NCT00365209
Locations
🇺🇸

Chao Family Comprehensive Cancer Center, Orange, California, United States

Phase III Trial of Gemcitabine, Curcumin and Celebrex in Patients With Metastatic Colon Cancer

Phase 3
Conditions
Colon Neoplasm
First Posted Date
2006-02-22
Last Posted Date
2006-02-22
Lead Sponsor
Tel-Aviv Sourasky Medical Center
Target Recruit Count
100
Registration Number
NCT00295035

Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients

Phase 2
Withdrawn
Conditions
Familial Adenomatous Polyposis
Interventions
Drug: curcumin
First Posted Date
2005-11-03
Last Posted Date
2012-09-20
Lead Sponsor
Johns Hopkins University
Registration Number
NCT00248053

Pharmacokinetics of Curcumin in Healthy Volunteers

Not Applicable
Completed
Conditions
Healthy
First Posted Date
2005-09-16
Last Posted Date
2020-11-03
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
6
Registration Number
NCT00181662
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

The Effects of Curcuminoids on Aberrant Crypt Foci in the Human Colon

Not Applicable
Terminated
Conditions
Aberrant Crypt Foci
First Posted Date
2005-09-15
Last Posted Date
2009-12-11
Lead Sponsor
University of Medicine and Dentistry of New Jersey
Target Recruit Count
60
Registration Number
NCT00176618
Locations
🇺🇸

Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

Curcumin (Diferuloylmethane Derivative) With or Without Bioperine in Patients With Multiple Myeloma

Not Applicable
Completed
Conditions
Multiple Myeloma
Interventions
Drug: Curcumin
Drug: Bioperine
First Posted Date
2005-06-13
Last Posted Date
2011-11-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
42
Registration Number
NCT00113841
Locations
🇺🇸

U.T.M.D. Anderson Cancer Center, Houston, Texas, United States

Trial of Curcumin in Advanced Pancreatic Cancer

Phase 2
Completed
Conditions
Pancreatic Neoplasms
Adenocarcinoma
Interventions
Drug: Curcumin
First Posted Date
2004-10-19
Last Posted Date
2020-08-28
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
50
Registration Number
NCT00094445
Locations
🇺🇸

UT MD Anderson Cancer Center, Houston, Texas, United States

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy