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Sebetralstat

Generic Name
Sebetralstat
Drug Type
Small Molecule
Chemical Formula
C26H26FN5O4
CAS Number
1933514-13-6
Unique Ingredient Identifier
O5ZD2TU2B7

Treatment of Angioedema Attacks in Adolescent and Adult Patients 12 Years and Older With HAE Type I or II With Sebetralstat

Conditions
Hereditary Angioedema
First Posted Date
2024-10-08
Last Posted Date
2025-01-20
Lead Sponsor
KalVista Pharmaceuticals, Ltd.
Registration Number
NCT06628713
Locations
🇺🇸

KalVista Investigative Site, Scottsdale, Arizona, United States

A Single Dose Safety, Tolerability, Pharmacokinetic and Food Effect Study of KVD900 (Sebetralstat) in Healthy Volunteers

Phase 1
Completed
Conditions
Hereditary Angioedema
Interventions
Drug: Placebo to KVD900
First Posted Date
2020-04-16
Last Posted Date
2025-04-29
Lead Sponsor
KalVista Pharmaceuticals, Ltd.
Target Recruit Count
84
Registration Number
NCT04349800
Locations
🇬🇧

KalVista Investigative Site, Wales, United Kingdom

A Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or II

Phase 2
Completed
Conditions
Hereditary Angioedema
Interventions
Other: Placebo
First Posted Date
2019-12-23
Last Posted Date
2025-05-02
Lead Sponsor
KalVista Pharmaceuticals, Ltd.
Target Recruit Count
84
Registration Number
NCT04208412
Locations
🇬🇧

KalVista Investigative Site, Newcastle, United Kingdom

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