MedPath

Calcium

Generic Name
Calcium
Drug Type
Small Molecule
Chemical Formula
Ca
CAS Number
7440-70-2
Unique Ingredient Identifier
SY7Q814VUP
Background

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.

Indication

Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.

Associated Conditions
Calcium Deficiency, Deficiency, Vitamin D, Osteodystrophy, Osteomalacia, Osteoporosis, Chronic Hypocalcemia, Chronic Hypocalcemia caused by anticonvulsant medications
Associated Therapies
Care of the Joint, Mineral supplementation therapy, Nutritional supplementation

Assessment of the Efficacy of Calcium Dobesilate vs. Placebo on SARS-CoV-2 Viral Load Amongst Outpatients With COVID-19.

Phase 2
Completed
Conditions
COVID-19 Virus Disease
Interventions
First Posted Date
2022-03-31
Last Posted Date
2024-02-28
Lead Sponsor
Hervé SPECHBACH
Target Recruit Count
74
Registration Number
NCT05305508
Locations
🇨🇭

Division and Department of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland

Effects of Denosumab on Bone Fusion in Osteoporotic Patients After Lumbar Fusion

Phase 4
Conditions
Fusion of Spine, Lumbar Region
Osteoporosis
Interventions
First Posted Date
2022-01-24
Last Posted Date
2022-01-24
Lead Sponsor
Shanghai Changzheng Hospital
Target Recruit Count
116
Registration Number
NCT05203588
Locations
🇨🇳

Shanghai Changzheng Hospital, Shanghai, Shanghai, China

Ovarian Hyperstimulation Syndrome Using Calcium Infusion

Not Applicable
Conditions
Ovarian Hyperstimulation Syndrome
Interventions
First Posted Date
2022-01-20
Last Posted Date
2022-02-22
Lead Sponsor
Al-Azhar University
Target Recruit Count
200
Registration Number
NCT05198128

The Effect of Vitamin D and Calcium Supplementation on the Prevention of Stress Fractures.

Not Applicable
Conditions
Stress Fracture
Vitamin d
Interventions
First Posted Date
2022-01-11
Last Posted Date
2022-01-11
Lead Sponsor
Xijing Hospital
Target Recruit Count
240
Registration Number
NCT05186194
Locations
🇨🇳

Department of Orthopedics, Xijing Hospital, The Air Force Medical University, Xi'an, Shanxi, China

Effect of HMP on Diabetic Microangiopaemia in T2DM

Phase 4
Completed
Conditions
Diabetes Mellitus, Type 2
Diabetic Angiopathies
Interventions
First Posted Date
2021-10-27
Last Posted Date
2024-07-09
Lead Sponsor
Affiliated Hospital of Nantong University
Target Recruit Count
40
Registration Number
NCT05095922
Locations
🇨🇳

Affiliated Hospital of Nantong University, Nantong, Jiangsu, China

Effects of Low Dose Aspirin in Bipolar Disorder (The A-Bipolar RCT)

Phase 2
Completed
Conditions
Bipolar Disorder
Interventions
First Posted Date
2021-09-05
Last Posted Date
2025-01-29
Lead Sponsor
Lars Vedel Kessing
Target Recruit Count
250
Registration Number
NCT05035316
Locations
🇩🇰

Psychiatric Center Copenhagen, Copenhagen, Denmark

Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .

Phase 4
Conditions
Necrotic Pulp With Symptomatic Apical Periodontitis
Interventions
First Posted Date
2021-08-26
Last Posted Date
2022-03-22
Lead Sponsor
Suez Canal University
Target Recruit Count
60
Registration Number
NCT05021809
Locations
🇪🇬

Endodontic Clinic At Faculty of Dentistry ,Suez Canal University, Ismailia, Egypt

Tangningtongluo Tablet in the Treatment of Non-proliferative Diabetic Retinopathy

Phase 2
Active, not recruiting
Conditions
Type2 Diabetes
Diabetic Retinopathy
Interventions
Drug: Tangningtongluo tablets
First Posted Date
2021-08-16
Last Posted Date
2023-05-09
Lead Sponsor
Guizhou Bailing Group Pharmaceutical Co Ltd
Target Recruit Count
240
Registration Number
NCT05007262
Locations
🇨🇳

Gansu Provincial Hospital of traditional Chinese Medicine, Lanzhou, Gansu, China

🇨🇳

Chongqing hospital of traditional Chinese Medicine, Chongqing, Chongqing, China

🇨🇳

People's Hospital of Anshun City Guizhou Province, Anshun, Guizhou, China

and more 10 locations

Propolis Versus Calcium Hydroxide on Post-Operative Pain in Patients With Necrotic Pulp

Not Applicable
Completed
Conditions
Post-Operative Pain, Chronic
Necrotic Pulp
Interventions
Dietary Supplement: propolis
First Posted Date
2021-07-30
Last Posted Date
2021-07-30
Lead Sponsor
Cairo University
Target Recruit Count
46
Registration Number
NCT04983524

Bioavailability and Pharmacokinetics of Calcium Dobesilate (Doxium®) in the Nasal Mucosal Tissue, Saliva and Blood of Treated Patients

Conditions
Biological Availability
Interventions
First Posted Date
2021-06-11
Last Posted Date
2021-06-11
Lead Sponsor
University Hospital, Geneva
Target Recruit Count
14
Registration Number
NCT04922996
Locations
🇨🇭

HUG, Geneva, Switzerland

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