Idarubicin

Generic Name
Idarubicin
Brand Names
Idamycin
Drug Type
Small Molecule
Chemical Formula
C26H27NO9
CAS Number
58957-92-9
Unique Ingredient Identifier
ZRP63D75JW
Background

An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.

Indication

For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.

Associated Conditions
Acute Myeloid Leukemia
Associated Therapies
-

Phase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

First Posted Date
2008-04-11
Last Posted Date
2015-03-09
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
106
Registration Number
NCT00656617
Locations
🇺🇸

The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States

A Study of LY2181308 Sodium in Patients With Relapsed or Refractory Acute Myeloid Leukemia

First Posted Date
2008-02-21
Last Posted Date
2019-09-09
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
24
Registration Number
NCT00620321
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Houston, Texas, United States

Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006)

First Posted Date
2007-10-12
Last Posted Date
2018-08-23
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
78
Registration Number
NCT00542971
Locations
🇺🇸

The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States

Idarubicin and High-Dose Cytarabine in Treating Patients With Acute Myeloid Leukemia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2007-09-12
Last Posted Date
2017-02-06
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
111
Registration Number
NCT00528398
Locations
🇺🇸

Banner Good Samaritan Medical Center, Phoenix, Arizona, United States

🇺🇸

City of Hope Comprehensive Cancer Center, Duarte, California, United States

Tretinoin and Arsenic Trioxide With or Without Idarubicin in Treating Patients With Acute Promyelocytic Leukemia

First Posted Date
2007-09-12
Last Posted Date
2016-01-29
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
1
Registration Number
NCT00528450
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

VELCADE in Combination With Idarubicin and Cytosine Arabinoside in Patients With Acute Myelogenous Leukemia

Phase 1
Completed
Conditions
First Posted Date
2007-07-23
Last Posted Date
2010-09-24
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
36
Registration Number
NCT00505700
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Beth Israel/ Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

SMD_FLAG-IDA_98: FLAG-IDA in Induction Treatment of High Risk Myelodysplastic Syndromes or Secondary Acute Myeloblastic Leukemia

First Posted Date
2007-06-18
Last Posted Date
2008-11-19
Lead Sponsor
PETHEMA Foundation
Target Recruit Count
200
Registration Number
NCT00487448
Locations
🇪🇸

Hospital Germans Trias i Pujol, Badalona, Spain

🇪🇸

Hospital Universitario La Paz, Madrid, Spain

🇪🇸

Hospital del Mar, Barcelona, Spain

and more 12 locations

Phase III Trial in Acute Promyelocytic Leukemia Patients

First Posted Date
2007-06-05
Last Posted Date
2022-10-12
Lead Sponsor
Gruppo Italiano Malattie EMatologiche dell'Adulto
Target Recruit Count
276
Registration Number
NCT00482833
Locations
🇦🇹

Universitätsklinik Innsbruck Hämatologie Onkologie, Innsbruck, Austria

🇦🇹

Krankenhaus der Barmherzigen Schwestern Linz, Linz, Austria

🇦🇹

Universitätsklinik für Innere Medizin III Salzburg, Salzburg, Austria

and more 106 locations

Lestaurtinib, Cytarabine, and Idarubicin in Treating Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia

Phase 1
Completed
Conditions
Interventions
First Posted Date
2007-05-07
Last Posted Date
2017-03-15
Lead Sponsor
Children's Oncology Group
Target Recruit Count
14
Registration Number
NCT00469859
Locations
🇺🇸

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas, Texas, United States

🇺🇸

Children's Hospital of Orange County, Orange, California, United States

🇺🇸

St. Jude Children's Research Hospital, Memphis, Tennessee, United States

and more 18 locations
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