Idarubicin

Generic Name
Idarubicin
Brand Names
Idamycin
Drug Type
Small Molecule
Chemical Formula
C26H27NO9
CAS Number
58957-92-9
Unique Ingredient Identifier
ZRP63D75JW
Background

An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.

Indication

For the treatment of acute myeloid leukemia (AML) in adults. This includes French-American-British (FAB) classifications M1 through M7.

Associated Conditions
Acute Myeloid Leukemia
Associated Therapies
-

Amifostine and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

First Posted Date
2003-01-27
Last Posted Date
2013-08-02
Lead Sponsor
Sidney Kimmel Cancer Center at Thomas Jefferson University
Registration Number
NCT00003268
Locations
🇺🇸

Kimmel Cancer Center of Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States

Chemotherapy in Treating Children With Recurrent Acute Myeloid Leukemia

First Posted Date
2003-01-27
Last Posted Date
2014-07-25
Lead Sponsor
Children's Oncology Group
Target Recruit Count
120
Registration Number
NCT00003178
Locations
🇺🇸

Simmons Cancer Center - Dallas, Dallas, Texas, United States

🇺🇸

Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, United States

🇺🇸

Children's Memorial Hospital - Chicago, Chicago, Illinois, United States

and more 231 locations

Chemotherapy, Interferon, and Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia

Phase 3
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-02
Lead Sponsor
German CML Study Group
Target Recruit Count
750
Registration Number
NCT00002771
Locations
🇩🇪

III Medizinische Klinik Mannheim, Mannheim, Germany

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2010-06-22
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Registration Number
NCT00002517
Locations
🇫🇷

Centre Hospitalier Regional et Universitaire d'Angers, Angers, France

🇧🇪

Algemeen Ziekenhuis Middelheim, Antwerp, Belgium

🇧🇪

Hopital Universitaire Des Enfants Reine Fabiola, Brussels, Belgium

and more 20 locations

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

First Posted Date
2003-01-27
Last Posted Date
2010-05-27
Lead Sponsor
European Organisation for Research and Treatment of Cancer - EORTC
Target Recruit Count
80
Registration Number
NCT00002926
Locations
🇧🇪

Hopital Universitaire Erasme, Brussels, Belgium

🇧🇪

Cliniques Universitaires Saint-Luc, Brussels, Belgium

🇨🇿

Institute of Hematology and Blood Transfusion, Prague, Czech Republic

and more 37 locations

Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma

First Posted Date
2003-01-27
Last Posted Date
2013-09-20
Lead Sponsor
Riverside Haematology Group
Target Recruit Count
660
Registration Number
NCT00003603
Locations
🇬🇧

Hammersmith Hospital, London, England, United Kingdom

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