Indomethacin
- Generic Name
- Indomethacin
- Brand Names
- Indocin, Tivorbex
- Drug Type
- Small Molecule
- Chemical Formula
- C19H16ClNO4
- CAS Number
- 53-86-1
- Unique Ingredient Identifier
- XXE1CET956
- Background
Indometacin, or indomethacin, is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic properties. NSAIDs consist of agents that are structurally unrelated; the NSAID chemical classification of indometacin is an indole-acetic acid derivative with the chemical name 1- (p-chlorobenzoyl)25-methoxy-2-methylindole-3-ace...
- Indication
Oral indometacin is indicated for symptomatic management of moderate to severe rheumatoid arthritis including acute flares of chronic disease, moderate to severe ankylosing spondylitis, moderate to severe osteoarthritis, acute painful shoulder (bursitis and/or tendinitis) and acute gouty arthritis.
...
- Associated Conditions
- Acute Gouty Arthritis, Joint Pain, Moderate to Severe Osteoarthritis, Moderate to Severe Rheumatoid Arthritis, Moderate to severe ankylosing spondylitis, Myalgia, Patent Ductus Arteriosus (PDA), Acute Shoulder Pain
- Associated Therapies
- -
Indomethacin Decreases Post-ERCP Pancreatitis
- Conditions
- Interventions
- First Posted Date
- 2014-04-10
- Last Posted Date
- 2015-03-24
- Lead Sponsor
- Instituto Mexicano del Seguro Social
- Target Recruit Count
- 160
- Registration Number
- NCT02110810
- Locations
- 🇲🇽
Department of Gastrointestinal Endoscopy and Department of Gastroenterology of the Specialties Hospital of the Western Medical Center of the Mexican Institute of Social Security., Guadalajara, Jalisco, Mexico
Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief
- First Posted Date
- 2013-10-08
- Last Posted Date
- 2015-06-15
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 270
- Registration Number
- NCT01957215
- Locations
- 🇨🇳
Changzhou NO.2 People?s Hospital, Changzhou, Jiangsu, China
🇨🇳Zhongda Hospital Southeast University, Nanjing, Jiangsu, China
🇨🇳The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Indomethacin for Tocolysis of Preterm Labor
- First Posted Date
- 2013-06-05
- Last Posted Date
- 2021-12-07
- Lead Sponsor
- MetroHealth Medical Center
- Registration Number
- NCT01869361
- Locations
- 🇺🇸
MetroHealth Medical Center, Cleveland, Ohio, United States
The Influence of Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Passive Heat Stress
- Conditions
- Interventions
- First Posted Date
- 2013-05-07
- Last Posted Date
- 2018-01-29
- Lead Sponsor
- Brock University
- Target Recruit Count
- 8
- Registration Number
- NCT01848665
- Locations
- 🇨🇦
Brock University, St Catharines, Ontario, Canada
Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress
- Conditions
- Interventions
- First Posted Date
- 2013-04-12
- Last Posted Date
- 2018-01-29
- Lead Sponsor
- Brock University
- Target Recruit Count
- 8
- Registration Number
- NCT01830335
- Locations
- 🇨🇦
Brock University, St Catharines, Ontario, Canada
Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
- First Posted Date
- 2013-01-24
- Last Posted Date
- 2016-11-04
- Lead Sponsor
- Dartmouth-Hitchcock Medical Center
- Target Recruit Count
- 449
- Registration Number
- NCT01774604
- Locations
- 🇺🇸
Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States
Electrophilic Fatty Acid Derivatives in Asthma
- Conditions
- Interventions
- First Posted Date
- 2012-11-27
- Last Posted Date
- 2017-07-11
- Lead Sponsor
- Sally E. Wenzel MD
- Target Recruit Count
- 50
- Registration Number
- NCT01733485
- Locations
- 🇺🇸
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
Phase I Platinum Based Chemotherapy Plus Indomethacin
- Conditions
- Interventions
- First Posted Date
- 2012-11-01
- Last Posted Date
- 2017-08-18
- Lead Sponsor
- UMC Utrecht
- Target Recruit Count
- 13
- Registration Number
- NCT01719926
- Locations
- 🇳🇱
Meander Medisch Centrum, Amersfoort, Utrecht, Netherlands
🇳🇱the Netherlands Cancer Institute, Amsterdam, Netherlands
🇨🇭Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
Study of Indomethacin Capsules to Treat Pain Following Bunionectomy
- Conditions
- Interventions
- First Posted Date
- 2012-06-22
- Last Posted Date
- 2014-03-17
- Lead Sponsor
- Iroko Pharmaceuticals, LLC
- Target Recruit Count
- 373
- Registration Number
- NCT01626118
- Locations
- 🇺🇸
Premier Research Group Limited, Salt Lake City, Utah, United States
🇺🇸Chesapeake Research Group, LLC, Pasadena, Maryland, United States
Evaluation of the Use of Indomethacin as Co-treatment in Women With Preterm Labor and High Risk of Intraamniotic Inflammation
- Conditions
- Interventions
- First Posted Date
- 2012-04-13
- Last Posted Date
- 2014-10-21
- Lead Sponsor
- Sara Varea
- Target Recruit Count
- 16
- Registration Number
- NCT01577121
- Locations
- 🇪🇸
Hospital Clinic of Barcelona- Maternity, Barcelona, Spain
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.