Bromocriptine
- Generic Name
- Bromocriptine
- Brand Names
- Cycloset, Parlodel
- Drug Type
- Small Molecule
- Chemical Formula
- C32H40BrN5O5
- CAS Number
- 25614-03-3
- Unique Ingredient Identifier
- 3A64E3G5ZO
- Background
Bromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity. It inhibits prolactin secretion and may be used to treat dysfunctions associated with hyperprolactinemia. Bromocriptine is also indicated for the management of signs and symptoms of Parkinsonian Syndrome, as well as the treatment of acromegaly. Bromocriptin...
- Indication
For the treatment of galactorrhea due to hyperprolactinemia, prolactin-dependent menstrual disorders and infertility, prolactin-secreting adenomas, prolactin-dependent male hypogonadism, as adjunct therapy to surgery or radiotherapy for acromegaly or as monotherapy is special cases, as monotherapy in early Parksinsonian Syndrome or as an adjunct with levodop...
- Associated Conditions
- Acromegaly, Hyperprolactinemia, Parkinson's Disease (PD), Type 2 Diabetes Mellitus, Neuroleptic malignant syndrome (NMS)
- Associated Therapies
- -
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy
- First Posted Date
- 2022-01-06
- Last Posted Date
- 2024-08-07
- Lead Sponsor
- Dennis M. McNamara, MD, MS
- Target Recruit Count
- 250
- Registration Number
- NCT05180773
- Locations
- 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸University of Texas Southwestern Medical Center, Dallas, Texas, United States
Repurposing Bromocriptine for Abeta Metabolism in Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2020-06-02
- Last Posted Date
- 2022-04-07
- Lead Sponsor
- Kyoto University
- Target Recruit Count
- 8
- Registration Number
- NCT04413344
- Locations
- 🇯🇵
Asakayama Hospital, Sakai, Osaka, Japan
🇯🇵Tokushima University Hospital, Tokushima, Japan
🇯🇵Tokyo Metropolitan Geriatric Hospital, Tokyo, Japan
Management of Ovarian Hyperstimulation Syndrome as a State of Defective Mineralocorticoid Response
- Conditions
- Interventions
- First Posted Date
- 2020-04-17
- Last Posted Date
- 2020-04-17
- Lead Sponsor
- Ganin Fertility Center
- Target Recruit Count
- 107
- Registration Number
- NCT04351126
- Locations
- 🇪🇬
Ganin Fertility Center, Cairo, Maadi, Egypt
Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa
- Conditions
- Interventions
- First Posted Date
- 2019-10-16
- Last Posted Date
- 2024-10-08
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 31
- Registration Number
- NCT04128683
- Locations
- 🇺🇸
University of California San Diego, San Diego, California, United States
Satisfaction of Patients With the Chosen Method of Inhibition of Lactation
- Conditions
- Interventions
- First Posted Date
- 2019-07-31
- Last Posted Date
- 2019-07-31
- Lead Sponsor
- Żelazna Medical Centre, LLC
- Target Recruit Count
- 90
- Registration Number
- NCT04038749
- Locations
- 🇵🇱
Żelazna Medical Centre, Warsaw, Poland
Bromocriptine for Patients with Schizophrenia and Prediabetes
- First Posted Date
- 2018-07-02
- Last Posted Date
- 2024-11-14
- Lead Sponsor
- VA Pittsburgh Healthcare System
- Target Recruit Count
- 15
- Registration Number
- NCT03575000
- Locations
- 🇺🇸
VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, United States
Dopamine Action on Metabolism in Relation to Genotype
- First Posted Date
- 2018-05-15
- Last Posted Date
- 2024-02-02
- Lead Sponsor
- University Hospital Tuebingen
- Target Recruit Count
- 150
- Registration Number
- NCT03525002
- Locations
- 🇩🇪
University of Tuebingen, Department of Internal Medicine IV, Tübingen, Germany
🇩🇪University Hospital Cologne, Cologne, Germany
🇩🇪University Hospital Luebeck, Luebeck, Germany
Dopaminergic Modulation of Frontostriatal Function With a Dopamine Agonist and COMT Inhibitor
- First Posted Date
- 2016-10-11
- Last Posted Date
- 2021-11-16
- Lead Sponsor
- University of California, Berkeley
- Registration Number
- NCT02929485
- Locations
- 🇺🇸
University of California, San Francisco, San Francisco, California, United States
🇺🇸University of California, Berkeley, Berkeley, California, United States
Efficacy and Safety of Dexamethasone Prevention for Patients of Ovarian Hyperstimulation Syndrome
- Conditions
- Interventions
- First Posted Date
- 2016-07-27
- Last Posted Date
- 2016-07-27
- Lead Sponsor
- Sun Yat-sen University
- Target Recruit Count
- 200
- Registration Number
- NCT02846493
- Locations
- 🇨🇳
The Sixth Affiliated Hospital,Sun Yat-Sen University, Guangzhou, Guangdong, China
Bromocriptine-QR Therapy on Sympathetic Tone and Vascular Biology in Type 2 Diabetes Subjects
- First Posted Date
- 2016-02-17
- Last Posted Date
- 2021-12-10
- Lead Sponsor
- Eastern Virginia Medical School
- Target Recruit Count
- 84
- Registration Number
- NCT02682901
- Locations
- 🇺🇸
Eastern Virgnia Medical School, Strelitz Diabetes Center, Norfolk, Virginia, United States
Drug Development Updates
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