Levomefolic acid

Generic Name
Levomefolic acid
Brand Names
Beyaz 28 Day, EnBrace HR, EnLyte, Safyral 28 Day, Tydemy 28 Day, Yaz Plus
Drug Type
Small Molecule
Chemical Formula
C20H25N7O6
CAS Number
31690-09-2
Unique Ingredient Identifier
8S95DH25XC
Background

Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues where it plays an essential role in the DNA synthesis, cyst...

Indication

For the treatment and prevention of folate deficiency and for use as an antidote against folic acid antagonists. Contained in oral contraceptives to reduce the risk of neural tube defects arising from folic acid deficiency for pregnant women who conceived during use or shortly after the discontinuation of the product. Being studied for use as a treatment for...

Associated Conditions
-
Associated Therapies
Nutritional supplementation

Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot Study

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-01-23
Last Posted Date
2024-01-24
Lead Sponsor
Queen's University
Target Recruit Count
10
Registration Number
NCT06218030
Locations
🇨🇦

Kingston Health Sciences Centre, Kingston, Ontario, Canada

L-methylfolate Supplementation to OROS-Methylphenidate Pharmacotherapy in ADHD Adults

First Posted Date
2013-05-14
Last Posted Date
2017-11-14
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
47
Registration Number
NCT01853280
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Combination Deplin® and Antidepressant Therapy for a Major Depressive Episode (MDE)- a Retrospective Analysis

First Posted Date
2009-10-26
Last Posted Date
2013-12-19
Lead Sponsor
Pamlab, Inc.
Target Recruit Count
242
Registration Number
NCT01001559
Locations
🇺🇸

Red Oak Psychiatry Associates, PA, Houston, Texas, United States

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