MedPath

Activated charcoal

Generic Name
Activated charcoal
Brand Names
Actidose, Insta-char
Drug Type
Small Molecule
Chemical Formula
C
CAS Number
64365-11-3
Unique Ingredient Identifier
2P3VWU3H10

Overview

Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances. It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive oral ingestion of certain medications or poisons by absorbing most drugs and toxins. However its effects is rendered poor on some compounds including strong acids or bases, methanol and substances with limited absorptive capacity (including iron, lithium, arsenic). It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. The clinical applications of activated charcoal occured in the early 1800's. While this management for acute poisoning is considered fairly invasive, it is on the World Health Organization's List of Essential Medicines that includes the most important medications needed in a basic health system.

Indication

Used as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons.

Associated Conditions

  • Abdominal Cramping
  • Aerophagy
  • Bloating
  • Constipation
  • Delayed Transit Time
  • Flatulence
  • Belching
  • Meteorism

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2025/04/02
Phase 2
Recruiting
2024/08/30
Phase 2
Not yet recruiting
2024/01/23
Phase 4
Completed
State University of New York - Upstate Medical University
2023/11/21
Phase 3
Recruiting
2023/08/28
Phase 1
Recruiting
Javier Villaneuva-Meyer, MD
2022/09/14
Phase 2
Not yet recruiting
Waleed Khaild Rahman Kareem Al-kabi
2022/08/23
Not Applicable
UNKNOWN
2022/07/22
Phase 4
Not yet recruiting
2022/02/08
Phase 2
Active, not recruiting
2021/06/16
Phase 2
Withdrawn

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Peaceful Mountain, Inc.
43846-0039
TOPICAL
12 [hp_X] in 1 g
5/21/2025
VistaPharm, LLC
66689-201
ORAL
50 g in 240 mL
11/20/2023
Bestmade Natural Products
82969-5119
ORAL
3 [hp_X] in 62.5 mg
6/5/2025
VistaPharm, LLC
66689-202
ORAL
50 g in 240 mL
11/20/2023
HF Acquisition Co LLC, DBA HealthFirst
51662-1200
ORAL
208 mg in 1 mL
2/19/2020
Deseret Biologicals, Inc.
43742-2178
ORAL
12 [hp_X] in 1 mL
4/22/2025
VistaPharm, LLC
66689-203
ORAL
50 g in 240 mL
11/20/2023
Uriel Pharmacy Inc.
48951-3020
ORAL
20 [hp_X] in 1 mL
8/12/2025
King Bio Inc.
57955-2828
ORAL
10 [hp_X] in 59 mL
5/20/2025
Aspen Veterinary Resources, Ltd.
46066-313
ORAL
55 [arb'U] in 1 mL
6/6/2025

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
NORIT TABLET 125 mg
SIN06063P
TABLET
125 mg
6/3/1991
NORIT CAPSULE 200 mg
SIN05799P
CAPSULE
200 mg
5/7/1991
ULTRACARBON TABLET 250 mg
SIN05853P
TABLET
250 mg
5/20/1991
CHARCOAL TABLET 200 mg
SIN10625P
TABLET
200 mg
1/7/1999

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
CHARACTOL-25
omega laboratories limited
02060205
Suspension - Oral
200 MG / ML
12/31/1985
CHARCO CAPS
dse healthcare solutions llc
02423715
Capsule - Oral
260 MG
1/15/2016
CHARACTOL-50
omega laboratories limited
00649236
Suspension - Oral
50 G / 250 ML
12/31/1985
LM-TONIC III
bio active canada ltd.
02233646
Liquid - Oral
12 X
1/19/1998
ACTIVATED ENZYME CONCENTRATE
malabar formulas
00603929
Tablet - Oral
50 MG
12/31/1983
ADAPTAGEN
bio active canada ltd.
02233546
Liquid - Oral
12 X
5/26/1998
CARBO VEGETABILIS D30 DPS
dr reckeweg canada
02078023
Drops - Oral
30 D / ML
12/31/1994
CHARAC-50
omega laboratories limited
00637955
Suspension - Oral
50 G / 225 ML
12/31/1985
CARBO VEGETABILIS
curanderos ltd.
02232506
Granules ,  Liquid ,  Tablet ,  Powder ,  Drops ,  Pellet ,  Globules - Oral
3 X
5/25/1998
ACTIVATED CHARCOAL
02420694
Capsule - Oral
225 MG
2/1/2019

CIMA AEMPS Drug Approvals

Approved Product
Company
Registration Number
Pharmaceutical Form
Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product
Company
Registration Number
Dosage Form
Strength
Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name
MA Holder
MA Number
Pharmaceutical Form
Active Ingredient
Authorization Date
No UK EMC drug information found for this drug.

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