MedPath

Activated charcoal

Generic Name
Activated charcoal
Brand Names
Actidose, Insta-char
Drug Type
Small Molecule
Chemical Formula
C
CAS Number
64365-11-3
Unique Ingredient Identifier
2P3VWU3H10

Overview

Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances. It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive oral ingestion of certain medications or poisons by absorbing most drugs and toxins. However its effects is rendered poor on some compounds including strong acids or bases, methanol and substances with limited absorptive capacity (including iron, lithium, arsenic). It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. The clinical applications of activated charcoal occured in the early 1800's. While this management for acute poisoning is considered fairly invasive, it is on the World Health Organization's List of Essential Medicines that includes the most important medications needed in a basic health system.

Indication

Used as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons.

Associated Conditions

  • Abdominal Cramping
  • Aerophagy
  • Bloating
  • Constipation
  • Delayed Transit Time
  • Flatulence
  • Belching
  • Meteorism

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2025/04/02
Phase 2
Not yet recruiting
2024/08/30
Phase 2
Not yet recruiting
2024/01/23
Phase 4
Completed
State University of New York - Upstate Medical University
2023/11/21
Phase 3
Recruiting
2023/08/28
Phase 1
Recruiting
Javier Villaneuva-Meyer, MD
2022/09/14
Phase 2
Not yet recruiting
Waleed Khaild Rahman Kareem Al-kabi
2022/08/23
Not Applicable
UNKNOWN
2022/07/22
Phase 4
Not yet recruiting
2022/02/08
Phase 2
Active, not recruiting
2021/06/16
Phase 2
Withdrawn

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Peaceful Mountain, Inc.
43846-0039
TOPICAL
12 [hp_X] in 1 g
5/21/2025
VistaPharm, LLC
66689-201
ORAL
50 g in 240 mL
11/20/2023
Bestmade Natural Products
82969-5119
ORAL
3 [hp_X] in 62.5 mg
6/5/2025
VistaPharm, LLC
66689-202
ORAL
50 g in 240 mL
11/20/2023
HF Acquisition Co LLC, DBA HealthFirst
51662-1200
ORAL
208 mg in 1 mL
2/19/2020
Deseret Biologicals, Inc.
43742-2178
ORAL
12 [hp_X] in 1 mL
4/22/2025
VistaPharm, LLC
66689-203
ORAL
50 g in 240 mL
11/20/2023
King Bio Inc.
57955-2828
ORAL
10 [hp_X] in 59 mL
5/20/2025
Aspen Veterinary Resources, Ltd.
46066-313
ORAL
55 [arb'U] in 1 mL
6/6/2025

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
NORIT TABLET 125 mg
SIN06063P
TABLET
125 mg
6/3/1991
NORIT CAPSULE 200 mg
SIN05799P
CAPSULE
200 mg
5/7/1991
ULTRACARBON TABLET 250 mg
SIN05853P
TABLET
250 mg
5/20/1991
CHARCOAL TABLET 200 mg
SIN10625P
TABLET
200 mg
1/7/1999

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
Medicinal Charcoal Granules
国药准字HJ20220076
化学药品
颗粒剂
2/20/2023
Medicinal Charcoal Tablets
国药准字H33020476
化学药品
片剂
4/28/2020
Medicinal Charcoal Tablets
国药准字H11021126
化学药品
片剂
11/27/2020
Medicinal Charcoal Tablets
国药准字H31021642
化学药品
片剂
2/10/2020
Medicinal Charcoal Tablets
国药准字H13022797
化学药品
片剂
9/28/2020
Medicinal Charcoal Tablets
国药准字H33020477
化学药品
片剂
4/28/2020
Medicinal Charcoal Capsules
国药准字H10960103
化学药品
胶囊剂
9/28/2020

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

Help Us Improve

Your feedback helps us provide better drug information and insights.

© Copyright 2025. All Rights Reserved by MedPath