Overview
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Background
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
Indication
Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes.
Associated Conditions
- Acne
- Dental Cavity
- Dermabrasion
- Gingivitis
- Plaque, Dental
- Abrasions
- Bacterial skin infections
- Minor burns
- Oral infections
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2020/09/04 | Phase 4 | Completed | Centro Ortopedico y Quirurgico del Pie | ||
2018/08/22 | Phase 4 | Completed | University of Campinas, Brazil | ||
2017/06/19 | Phase 3 | Completed | University of Guarulhos | ||
2016/02/01 | Phase 4 | Completed | |||
2013/06/19 | N/A | Completed | |||
2011/10/24 | Phase 4 | UNKNOWN | |||
2010/02/19 | Phase 3 | Completed | |||
2009/11/16 | Phase 2 | Completed | |||
2008/10/02 | Phase 3 | Completed | |||
2008/09/30 | Phase 3 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| SAPI-SONS PHARMACEUTICAL INTERNATIONAL COSMETICS | 66854-004 | TOPICAL | 0.3 mg in 100 mL | 8/5/2012 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| QV FLARE UP BATH OIL | SIN11468P | LOTION | 2% w/w | 3/19/2001 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| ST. LUKE'S PRICKLY HEAT SOAP | N/A | N/A | N/A | 6/8/2009 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| MICROGUARD 401 1% W/W TRICLOSAN SOLUTION bottle | 202696 | Medicine | A | 11/5/2012 | |
| PHISOHEX triclosan 1% lotion bottle | 51227 | Medicine | A | 1/9/1995 | |
| DETTOL antiseptic cream tube | 15362 | Medicine | A | 9/30/1991 | |
| QV FLARE UP BATH OIL solution bottle | 142064 | Medicine | A | 7/12/2007 | |
| APURA PREPQARATION ANTIBACTERIAL CLEANSING GEL tube | 91424 | Medicine | A | 10/22/2002 | |
| MICROSHIELD T TRICLOSAN SKIN CLEANSER triclosan 10mg/g bottle | 71212 | Medicine | A | 10/13/1999 | |
| EVODERM T triclosan 1%w/w solution bottle | 337668 | Medicine | A | 6/10/2020 | |
| CUSSONS CAREX ANTIBACTERIAL MOISTURISING LIQUID HANDWASH lotion bottle | 58705 | Medicine | A | 1/24/1997 | |
| MICROSHIELD T TRICLOSAN SKIN CLEANSER triclosan 10mg/g bag | 71213 | Medicine | A | 10/13/1999 | |
| GAMOPHEN triclosan 1% MEDICATED SOAP | 44107 | Medicine | A | 5/6/1993 |