Triclosan
- Generic Name
- Triclosan
- Brand Names
- Dermaprot Triclotrex-B, Ting
- Drug Type
- Small Molecule
- Chemical Formula
- C12H7Cl3O2
- CAS Number
- 3380-34-5
- Unique Ingredient Identifier
- 4NM5039Y5X
- Background
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
- Indication
Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes.
- Associated Conditions
- Acne, Dental Cavity, Dermabrasion, Gingivitis, Plaque, Dental, Abrasions, Bacterial skin infections, Minor burns, Oral infections
- Associated Therapies
- Antibacterial therapy, Antibiotic pre-surgical prophylaxis
Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2010-12-28
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 44
- Registration Number
- NCT00762515
- Locations
- 🇺🇸
University of Louisville, School of Dentistry, Louisville, Kentucky, United States
Development of Clinical Method to Triclosan Retention in Plaque Following Brushing
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2012-02-17
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 20
- Registration Number
- NCT00762853
- Locations
- 🇹ðŸ‡
Mahidol University, Bangkok, Bangkok 10110, Thailand
Collection of Gingival Crevicular Fluid From Periodontitis Patients
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2011-06-14
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 39
- Registration Number
- NCT00763048
- Locations
- 🇺🇸
Forsyth Institute, Boston, Massachusetts, United States
Investigate Oral Bacteria in Adult Population
- Conditions
- Oral Bacteria
- Interventions
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2011-03-23
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 24
- Registration Number
- NCT00762177
- Locations
- 🇺🇸
Department of Oral Biology, Newark, New York, United States
Periodontal Disease and Cardiovascular Disease
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2008-10-02
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 438
- Registration Number
- NCT00763165
- Locations
- 🇦🇺
Discipline of Medicine, Chermside, Australia
Drug Development Updates
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