Triclosan
- Generic Name
- Triclosan
- Brand Names
- Dermaprot Triclotrex-B, Ting
- Drug Type
- Small Molecule
- Chemical Formula
- C12H7Cl3O2
- CAS Number
- 3380-34-5
- Unique Ingredient Identifier
- 4NM5039Y5X
- Background
An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.
- Indication
Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes.
- Associated Conditions
- Acne, Dental Cavity, Dermabrasion, Gingivitis, Plaque, Dental, Abrasions, Bacterial skin infections, Minor burns, Oral infections
- Associated Therapies
- Antibacterial therapy, Antibiotic pre-surgical prophylaxis
Pre-surgical Antisepsis of Hands After Washing With Triclosan 0.5% Compared to Propan-1-ol 60%
- Conditions
- Antisepsis
- Interventions
- First Posted Date
- 2020-09-04
- Last Posted Date
- 2020-11-02
- Lead Sponsor
- Centro Ortopedico y Quirurgico del Pie
- Target Recruit Count
- 24
- Registration Number
- NCT04538365
- Locations
- 🇪🇸
Facultad de Enfermeria, Fisioterapia y Podologia, Madrid, Spain
Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families.
- Conditions
- Generalized Aggressive Periodontitis
- Interventions
- Drug: Placebo
- First Posted Date
- 2018-08-22
- Last Posted Date
- 2018-10-02
- Lead Sponsor
- University of Campinas, Brazil
- Target Recruit Count
- 40
- Registration Number
- NCT03642353
- Locations
- 🇧🇷
University of Campinas, UNICAMP, Piracicaba, Sao Paulo, Brazil
Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment.
- Conditions
- Peri-ImplantitisPeriodontal Diseases
- Interventions
- Procedure: Surgical anti-infective therapyProcedure: Periodontal treatmentProcedure: Oral Hygiene InstructionDrug: Fluoride toothpasteProcedure: Regular maintenance program
- First Posted Date
- 2017-06-19
- Last Posted Date
- 2017-06-19
- Lead Sponsor
- University of Guarulhos
- Target Recruit Count
- 102
- Registration Number
- NCT03191721
- Locations
- 🇧🇷
Guarulhos University, Guarulhos, São Paulo, Brazil
🇧🇷State University of Maringa, Maringa, Santa Catarina, Brazil
Clinical Investigation of the Effects of Colgate Total Toothpaste as Compared to a Matching Placebo on Periodontal Disease and Systemic Inflammatory Markers
- Conditions
- Systemic Inflammatory MarkersPeriodontal Disease
- Interventions
- First Posted Date
- 2016-02-01
- Last Posted Date
- 2019-02-22
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 303
- Registration Number
- NCT02670135
Periodontal Treatment Response in Type II Diabetic Patients
- Conditions
- Type II DiabetesPeriodontal Disease
- Interventions
- Drug: Non-triclosan containing toothpaste
- First Posted Date
- 2013-06-19
- Last Posted Date
- 2018-09-17
- Lead Sponsor
- University of Florida
- Target Recruit Count
- 74
- Registration Number
- NCT01881074
- Locations
- 🇺🇸
University of Florida, Gainesville, Florida, United States
Effectiveness of Triclosan Coated Sutures in Preventing Leg Wound Infection After Coronary Artery Bypass Surgery
- Conditions
- Complication of Coronary Artery Bypass GraftSurgical Wound Infection
- Interventions
- Other: Conventional non-coated surgical sutures
- First Posted Date
- 2011-10-24
- Last Posted Date
- 2011-10-24
- Lead Sponsor
- Rambam Health Care Campus
- Target Recruit Count
- 410
- Registration Number
- NCT01457859
- Locations
- 🇮🇱
Rambam Health Care Campus, Depatment of cardiac surgery, Haifa, Israel
To Access the Effects of Mucositis in Adults With Dental Implants
- First Posted Date
- 2010-02-19
- Last Posted Date
- 2010-10-05
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 60
- Registration Number
- NCT01072201
- Locations
- 🇮🇹
Ariminum Research & Dental Education Center, Rimini, Italy
Evaluating Commercial Anti-Plaque Products and Oral Rinse
- Conditions
- Dental Plaque
- Interventions
- First Posted Date
- 2009-11-16
- Last Posted Date
- 2011-06-14
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 26
- Registration Number
- NCT01014143
- Locations
- 🇺🇸
New Institutional Service Company, Northfield, New Jersey, United States
Training and Calibration of Dental Examiners
- Conditions
- Dental Plaque
- Interventions
- First Posted Date
- 2008-10-02
- Last Posted Date
- 2008-10-03
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 18
- Registration Number
- NCT00765167
- Locations
- 🇺🇸
UMDNJ Dental School, Newark, New Jersey, United States
Compare the Clinical Efficacy of Prototype Toothpastes.
- Conditions
- Gingival Diseases
- Interventions
- First Posted Date
- 2008-09-30
- Last Posted Date
- 2013-08-15
- Lead Sponsor
- Colgate Palmolive
- Target Recruit Count
- 103
- Registration Number
- NCT00761930
- Locations
- 🇺🇸
Eastman Dental Center - University of Rochester, Rochester, New York, United States
Drug Development Updates
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