Triclosan

Generic Name
Triclosan
Brand Names
Dermaprot Triclotrex-B, Ting
Drug Type
Small Molecule
Chemical Formula
C12H7Cl3O2
CAS Number
3380-34-5
Unique Ingredient Identifier
4NM5039Y5X
Background

An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.

Indication

Triclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes.

Associated Conditions
Acne, Dental Cavity, Dermabrasion, Gingivitis, Plaque, Dental, Abrasions, Bacterial skin infections, Minor burns, Oral infections
Associated Therapies
Antibacterial therapy, Antibiotic pre-surgical prophylaxis

Triclosan as Adjunctive Therapy in the Plaque Control in Children From Generalized Aggressive Periodontitis Families.

First Posted Date
2018-08-22
Last Posted Date
2018-10-02
Lead Sponsor
University of Campinas, Brazil
Target Recruit Count
40
Registration Number
NCT03642353
Locations
🇧🇷

University of Campinas, UNICAMP, Piracicaba, Sao Paulo, Brazil

Effectiveness of Triclosan Coated Sutures in Preventing Leg Wound Infection After Coronary Artery Bypass Surgery

First Posted Date
2011-10-24
Last Posted Date
2011-10-24
Lead Sponsor
Rambam Health Care Campus
Target Recruit Count
410
Registration Number
NCT01457859
Locations
🇮🇱

Rambam Health Care Campus, Depatment of cardiac surgery, Haifa, Israel

Training and Calibration of Dental Examiners

First Posted Date
2008-10-02
Last Posted Date
2008-10-03
Lead Sponsor
Colgate Palmolive
Target Recruit Count
18
Registration Number
NCT00765167
Locations
🇺🇸

UMDNJ Dental School, Newark, New Jersey, United States

Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-09-30
Last Posted Date
2010-12-28
Lead Sponsor
Colgate Palmolive
Target Recruit Count
44
Registration Number
NCT00762515
Locations
🇺🇸

University of Louisville, School of Dentistry, Louisville, Kentucky, United States

Periodontal Disease and Cardiovascular Disease

First Posted Date
2008-09-30
Last Posted Date
2008-10-02
Lead Sponsor
Colgate Palmolive
Target Recruit Count
438
Registration Number
NCT00763165
Locations
🇦🇺

Discipline of Medicine, Chermside, Australia

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