Enzastaurin

Generic Name
Enzastaurin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C32H29N5O2
CAS Number
170364-57-5
Unique Ingredient Identifier
UC96G28EQF
Background

Enzastaurin, an investigational, targeted, oral agent, will be evaluated at more than 100 sites worldwide for the treatment of relapsed glioblastoma multiforme (GBM), an aggressive and malignant form of brain cancer.

Indication

Investigated for use/treatment in brain cancer, lymphoma (non-hodgkin's), and lung cancer.

Associated Conditions
-
Associated Therapies
-

First Line Chemotherapy Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)

First Posted Date
2006-03-30
Last Posted Date
2021-05-13
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
218
Registration Number
NCT00308750
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Houston, Texas, United States

Enzastaurin Versus Lomustine in Glioblastoma

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-02-24
Last Posted Date
2019-09-12
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
397
Registration Number
NCT00295815
Locations
🇬🇧

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Glasgow, Scotland, United Kingdom

Phase 2 Study of Gemcitabine or Gemcitabine + Enzastaurin in Participants With Advanced or Metastatic Pancreatic Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-12-20
Last Posted Date
2020-08-31
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
130
Registration Number
NCT00267020
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559), Mon - Fri, 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST) or speak with your personal physician, Dallas, Texas, United States

A Study of LY317615 in Patients With Brain Tumors

Phase 2
Completed
Conditions
First Posted Date
2005-09-19
Last Posted Date
2007-01-26
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
120
Registration Number
NCT00190723
Locations
🇺🇸

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon- Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician, Bethesda, Maryland, United States

Oral Enzastaurin in Participants With Relapsed Mantle Cell Lymphoma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2004-07-23
Last Posted Date
2020-07-01
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
60
Registration Number
NCT00088205
Locations
🇳🇱

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Monday-Friday from 9:00 AM to 5:00 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician, Rotterdam, Netherlands

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