Propranolol
- Generic Name
- Propranolol
- Brand Names
- Hemangeol, Hemangiol, Inderal, Innopran
- Drug Type
- Small Molecule
- Chemical Formula
- C16H21NO2
- CAS Number
- 525-66-6
- Unique Ingredient Identifier
- 9Y8NXQ24VQ
- Background
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.
Propranolol was granted FDA approval on 13 November 1967.
- Indication
Propranolol is indicated to treat hypertension. Propranolol is also indicated to treat angina pectoris due to coronary atherosclerosis, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, pheochromocytoma, and proliferating infantile hemangioma.
- Associated Conditions
- Akathisia caused by antipsychotic use, Angina Pectoris, Atrial Fibrillation, Cardiovascular Mortality, Essential Tremor, Gastroesophageal variceal hemorrhage prophylaxis, Hemangiomas, Hypertension, Migraine, Myocardial Infarction, Obstructive Hypertrophic Cardiomyopathy, Performance Anxiety, Pheochromocytoma, Proliferating Infantile Hemangioma, Supraventricular Arrhythmias, Tachyarrhythmia caused by Digitalis intoxication, Tachyarrhythmia caused by catecholamine excess, Thyroid Crisis, Thyrotoxicosis, Tremor caused by lithium, Ventricular Tachycardia (VT)
- Associated Therapies
- -
The Effect of Carvedilol Vs Propranolol in Cirrhotic Patients With Variceal Bleeding
- Conditions
- Interventions
- First Posted Date
- 2015-03-11
- Last Posted Date
- 2015-03-11
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 480
- Registration Number
- NCT02385422
- Locations
- 🇨🇳
Shanghai Zhongshan Hospital, Shanghai, Shanghai, China
Comparison of Propranolol and Venlafaxine in Treatment of Vestibular Migraine
- First Posted Date
- 2015-01-30
- Last Posted Date
- 2015-01-30
- Lead Sponsor
- Haseki Training and Research Hospital
- Target Recruit Count
- 73
- Registration Number
- NCT02350985
- Locations
- 🇹🇷
Haseki Training and Research Hospital, Istanbul, Turkey
Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma
- First Posted Date
- 2015-01-19
- Last Posted Date
- 2022-06-16
- Lead Sponsor
- West China Hospital
- Target Recruit Count
- 377
- Registration Number
- NCT02342275
- Locations
- 🇨🇳
West China Hospital of Sichuan University, Chengdu, Sichuan, China
The Effects of Propranolol on Fear of Tooth or Molar Extraction
- First Posted Date
- 2014-10-20
- Last Posted Date
- 2020-04-17
- Target Recruit Count
- 36
- Registration Number
- NCT02268357
- Locations
- 🇳🇱
Dept. of Oral and Maxillofacial Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
Effects on the Airway Lumen of Talsaclidine in Combination With Propranolol in Comparison to the Effects of the Monosubstances in Healthy Elderly Male Volunteers
- First Posted Date
- 2014-10-15
- Last Posted Date
- 2014-10-15
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 12
- Registration Number
- NCT02264093
In Vivo Specificity of KUC 7483 CL Co-administered With Bisoprolol, Propranolol, and Acipimox in Healthy Male Subjects
- Conditions
- Interventions
- First Posted Date
- 2014-10-06
- Last Posted Date
- 2014-10-06
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 12
- Registration Number
- NCT02256722
Effect of "Sekanjabin e Safarjali" (Quince Oxymel) in the Prevention of Migraine Attacks
- Conditions
- Interventions
- First Posted Date
- 2014-07-02
- Last Posted Date
- 2014-07-10
- Lead Sponsor
- Shiraz University of Medical Sciences
- Target Recruit Count
- 45
- Registration Number
- NCT02179775
- Locations
- 🇮🇷
Shiraz University of Medical Sciences, Shiraz, Fars, Iran, Islamic Republic of
Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
- Conditions
- Interventions
- First Posted Date
- 2014-06-24
- Last Posted Date
- 2018-04-18
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT02171988
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety
- Conditions
- Interventions
- First Posted Date
- 2014-06-03
- Last Posted Date
- 2023-04-11
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 142
- Registration Number
- NCT02153944
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Propranolol and Botulinum Toxin for Essential Vocal Tremor
- Conditions
- Interventions
- First Posted Date
- 2014-04-11
- Last Posted Date
- 2016-04-27
- Lead Sponsor
- Emory University
- Target Recruit Count
- 18
- Registration Number
- NCT02111369
- Locations
- 🇺🇸
Emory Voice Center, Atlanta, Georgia, United States
Drug Development Updates
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