Silver sulfadiazine
- Generic Name
- Silver sulfadiazine
- Brand Names
- Flamazine, Silvadene, Ssd, Thermazene
- Drug Type
- Small Molecule
- Chemical Formula
- C10H9AgN4O2S
- CAS Number
- 22199-08-2
- Unique Ingredient Identifier
- W46JY43EJR
- Background
Silver sulfadiazine is a sulfa derivative topical antibacterial used primarily on second- and third-degree burns.
- Indication
Indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.
- Associated Conditions
- Wound Infections
SWC for Treatment of Superficial Partial-Thickness Burns
- Conditions
- Burn Wounds
- Interventions
- Device: SynePure Wound Cleanser and Catasyn Advanced Technology Hydrogel
- First Posted Date
- 2023-05-26
- Last Posted Date
- 2024-12-03
- Lead Sponsor
- Synedgen, Inc.
- Target Recruit Count
- 2
- Registration Number
- NCT05877638
- Locations
- 🇺🇸
Louisiana State University Health Science Center at New Orleans, New Orleans, Louisiana, United States
StrataXRT for the Prevention and Treatment of Radiation Dermatitis in Breast Cancer or Head and Neck Cancer Patients
- Conditions
- Breast CarcinomaRadiation-Induced DermatitisHead and Neck Carcinoma
- Interventions
- Drug: Silicone-based Film Forming Topical GelOther: Petrolatum-Mineral Oil-Lanolin-Ceresin OintmentOther: Polyethylene Glycol Hydrogel
- First Posted Date
- 2021-10-11
- Last Posted Date
- 2024-05-06
- Lead Sponsor
- OHSU Knight Cancer Institute
- Registration Number
- NCT05073172
- Locations
- 🇺🇸
OHSU Knight Cancer Institute, Portland, Oregon, United States
Superficial Partial-Thickness Burn Study
- Conditions
- Superficial Partial Thickness Burn
- Interventions
- Device: Catasyn™ Advanced Technology Hydrogel and SynePure™ Wound Cleanser
- First Posted Date
- 2020-10-23
- Last Posted Date
- 2024-02-01
- Lead Sponsor
- J. Peter Rubin, MD
- Target Recruit Count
- 26
- Registration Number
- NCT04601532
- Locations
- 🇺🇸
UPMC Mercy Hospital, Pittsburgh, Pennsylvania, United States
Comparative Analysis of Cost-effectiveness of Silver Dressing in Burns
- Conditions
- Second-degree Burn
- Interventions
- First Posted Date
- 2014-04-09
- Last Posted Date
- 2021-05-18
- Lead Sponsor
- University of Sorocaba
- Target Recruit Count
- 100
- Registration Number
- NCT02108535
- Locations
- 🇧🇷
Clinic of the Burn Treatment of Sorocaba's Hospital Complex, Sorocaba, Sao Paulo, Brazil
Comparison of a Water-soluble Topical Antimicrobial to Silver Sulfadiazine in Partial Thickness Burns
- First Posted Date
- 2013-08-20
- Last Posted Date
- 2013-08-21
- Lead Sponsor
- University of Virginia
- Target Recruit Count
- 8
- Registration Number
- NCT01926392
- Locations
- 🇺🇸
University of Virginia Health System, Charlottesville, Virginia, United States
To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Deep Dermal Burn
- Conditions
- Burns
- Interventions
- Device: BCT Antimicrobial Dressing
- First Posted Date
- 2012-05-15
- Last Posted Date
- 2017-07-13
- Lead Sponsor
- Bio-medical Carbon Technology Co., Ltd.
- Target Recruit Count
- 30
- Registration Number
- NCT01598493
- Locations
- 🇨🇳
Burn Center, Department of Surgery, National Taiwan University Hospital, Taipei city, Taiwan
To Study the Healing Effect of Silver Impregnated Activated Carbon Fiber Wound Dressing on Superficial Dermal Burn
- Conditions
- Burns
- Interventions
- Device: BCT Antimicrobial Dressing
- First Posted Date
- 2012-05-15
- Last Posted Date
- 2017-07-13
- Lead Sponsor
- Bio-medical Carbon Technology Co., Ltd.
- Target Recruit Count
- 30
- Registration Number
- NCT01598480
- Locations
- 🇨🇳
Burn Center, Department of Surgery, National Taiwan University Hospital, Taipei City, Taiwan
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
- Conditions
- Burns
- Interventions
- Drug: Investigational Drug, MW-III
- First Posted Date
- 2011-02-16
- Last Posted Date
- 2025-01-13
- Lead Sponsor
- Skingenix, Inc.
- Target Recruit Count
- 60
- Registration Number
- NCT01297400
- Locations
- 🇺🇸
Valleywise Health Medical Center, Phoenix, Arizona, United States
🇺🇸University of CA Davis Medical Center, Sacramento, California, United States
🇺🇸MedStar Washington Hospital Center, Washington, District of Columbia, United States
Drug Development Updates
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