Benzoyl peroxide

Generic Name
Benzoyl peroxide
Brand Names
Acanya, Aktipak, Benzac, Benzaclin, Benzamycin, Benzefoam, Benzepro, Cabtreo, Clean and Clear, Clean and Clear Advantage Mark Treatment, Clearasil, Clindoxyl, Duac, Epiduo, Epsolay, Neobenz Micro Wash, Neuac, Onexton, Oxy Daily Wash, Panoxyl, Persa-gel, Relovox, Riax, SkinMedica Acne Treatment, Tactupump, Twyneo, Vanoxide-HC
Drug Type
Small Molecule
Chemical Formula
C14H10O4
CAS Number
94-36-0
Unique Ingredient Identifier
W9WZN9A0GM
Background

Benzoyl peroxide is a commonly used drug in topical treatments for acne. It has been formulated as products with either a single active ingredient, or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins. This treatment decreases keratin and se...

Indication

Benzoyl peroxide is formulated with antibiotics such as erythromycin and clindamycin for the treatment of acne vulgaris. Benzoyl peroxide is formulated as a number of topical products for the treatment of acne. Benzoyl peroxide is also indicated in combination with tretinoin for the treatment of acne vulgaris in patients aged nine years and older. A triple-c...

Associated Conditions
Acne, Acne Vulgaris, Inflammatory Acne Vulgaris, Inflammatory lesions caused by rosacea
Associated Therapies
-

A Clinical Trial Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris

First Posted Date
2008-04-22
Last Posted Date
2008-04-22
Lead Sponsor
Dow Pharmaceutical Sciences
Target Recruit Count
1399
Registration Number
NCT00663286
Locations
🇺🇸

Central Sooner Research, Norman, Oklahoma, United States

🇺🇸

Derm Center of Augusta, Augusta, Georgia, United States

🇺🇸

Webster Dermatology, PA, Hockessin, Delaware, United States

and more 29 locations

Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-04-14
Last Posted Date
2018-08-28
Lead Sponsor
Wake Forest University
Target Recruit Count
20
Registration Number
NCT00658112
Locations
🇺🇸

Wake Forest University Health Sciences Dermatology, Winston-Salem, North Carolina, United States

Study of Benzoyl Peroxide Cream for Mild to Moderate Acne Vulgaris

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2007-11-15
Last Posted Date
2017-09-26
Lead Sponsor
Northwestern University
Target Recruit Count
11
Registration Number
NCT00558831
Locations
🇺🇸

Northwestern University Department of Dermatology, Chicago, Illinois, United States

A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris

First Posted Date
2007-01-15
Last Posted Date
2021-02-18
Lead Sponsor
Galderma R&D
Target Recruit Count
1670
Registration Number
NCT00421993
Locations
🇺🇸

UTSW Medical Center at Dallas, Dallas, Texas, United States

🇺🇸

Dawes Fretzin Clinical Research Group, LLC, Indianapolis, Indiana, United States

🇺🇸

Dolby Research, LLC, Baton Rouge, Louisiana, United States

and more 58 locations
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