Benzoyl peroxide
- Generic Name
- Benzoyl peroxide
- Brand Names
- Acanya, Aktipak, Benzac, Benzaclin, Benzamycin, Benzefoam, Benzepro, Cabtreo, Clean and Clear, Clean and Clear Advantage Mark Treatment, Clearasil, Clindoxyl, Duac, Epiduo, Epsolay, Neobenz Micro Wash, Neuac, Onexton, Oxy Daily Wash, Panoxyl, Persa-gel, Relovox, Riax, SkinMedica Acne Treatment, Tactupump, Twyneo, Vanoxide-HC
- Drug Type
- Small Molecule
- Chemical Formula
- C14H10O4
- CAS Number
- 94-36-0
- Unique Ingredient Identifier
- W9WZN9A0GM
- Background
Benzoyl peroxide is a commonly used drug in topical treatments for acne. It has been formulated as products with either a single active ingredient, or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins. This treatment decreases keratin and se...
- Indication
Benzoyl peroxide is formulated with antibiotics such as erythromycin and clindamycin for the treatment of acne vulgaris. Benzoyl peroxide is formulated as a number of topical products for the treatment of acne. Benzoyl peroxide is also indicated in combination with tretinoin for the treatment of acne vulgaris in patients aged nine years and older. A triple-c...
- Associated Conditions
- Acne, Acne Vulgaris, Inflammatory Acne Vulgaris, Inflammatory lesions caused by rosacea
- Associated Therapies
- -
MC RCT - BPO vs Adapalene
- Conditions
- Interventions
- First Posted Date
- 2022-09-13
- Last Posted Date
- 2024-03-06
- Lead Sponsor
- University of Oklahoma
- Registration Number
- NCT05536882
- Locations
- 🇺🇸
OU Health Department of Dermatology, Oklahoma City, Oklahoma, United States
Cutibacterium Acnes in Deep Tissues in Primary Spine and Shoulder Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-05-02
- Last Posted Date
- 2022-05-02
- Lead Sponsor
- Hospital del Mar
- Target Recruit Count
- 200
- Registration Number
- NCT05355844
Profiling the Skin Microbiome in Response to Altreno in Acne Patients
- First Posted Date
- 2020-09-14
- Last Posted Date
- 2024-02-06
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Target Recruit Count
- 25
- Registration Number
- NCT04548349
- Locations
- 🇺🇸
Beth Israel Deacones Medical Center, Boston, Massachusetts, United States
Double-blind Placebo-controlled Trial of Generic Clindamycin/Benzoyl Peroxide Gel Versus Onexton Gel in Acne Vulgaris
- Conditions
- Interventions
- First Posted Date
- 2015-11-30
- Last Posted Date
- 2020-05-27
- Lead Sponsor
- Actavis Inc.
- Target Recruit Count
- 862
- Registration Number
- NCT02616614
- Locations
- 🇺🇸
Sundance Clinical Research, Saint Louis, Missouri, United States
🇺🇸Estudy, La Mesa, California, United States
🇺🇸Heartland Research Assoc, Wichita, Kansas, United States
Benzac 5% Gel in Combination With Cosmetic Products in Acne Vulgaris
- Conditions
- Interventions
- First Posted Date
- 2015-10-28
- Last Posted Date
- 2021-02-18
- Lead Sponsor
- Galderma R&D
- Target Recruit Count
- 50
- Registration Number
- NCT02589405
- Locations
- 🇩🇪
EGBERT Mi-Ran, Münster, Germany
A Bioequivalence Study With Clinical Endpoints Comparing Adapalene and Benzoyl Peroxide Topical Gel 0.1%/2.5% (Actavis Mid-Atlantic LLC) To Epiduo™ (Adapalene and Benzoyl Peroxide) Gel 0.1%/2.5% (Galderma Laboratories, L.P.) in the Treatment of Mild to Severe Acne Vulgaris
- Conditions
- Interventions
- First Posted Date
- 2011-12-29
- Last Posted Date
- 2011-12-29
- Lead Sponsor
- Actavis Mid-Atlantic LLC
- Target Recruit Count
- 885
- Registration Number
- NCT01501799
- Locations
- 🇧🇿
FXM Research International - Belize, Belize City, Belize
🇺🇸Haber Dermatology and Cosmetic Surgery Inc., South Euclid, Ohio, United States
🇺🇸Adult & Pediatric Dermatology, Overland Park, Kansas, United States
Comparing OTC Acne Treatment to Prescription Regimen
- First Posted Date
- 2010-11-10
- Last Posted Date
- 2019-07-16
- Lead Sponsor
- Milton S. Hershey Medical Center
- Target Recruit Count
- 66
- Registration Number
- NCT01237821
- Locations
- 🇺🇸
Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
Comparison of Nadifloxacin Cream Alone and With Benzoyl Peroxide Solution in the Treatment of Acne
- First Posted Date
- 2009-03-26
- Last Posted Date
- 2009-03-26
- Lead Sponsor
- Marmara University
- Target Recruit Count
- 90
- Registration Number
- NCT00869492
- Locations
- 🇹🇷
Marmara University school of medicine, Istanbul, Turkey
Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne
- First Posted Date
- 2009-02-11
- Last Posted Date
- 2017-05-25
- Lead Sponsor
- Stiefel, a GSK Company
- Target Recruit Count
- 54
- Registration Number
- NCT00841776
- Locations
- 🇺🇸
Skin We Care Dermatology, Mason, Ohio, United States
🇺🇸Dermatology Specialists, PSC, Louisville, Kentucky, United States
A Clinical Study Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris
- Conditions
- Interventions
- First Posted Date
- 2008-04-22
- Last Posted Date
- 2008-04-22
- Lead Sponsor
- Dow Pharmaceutical Sciences
- Target Recruit Count
- 1414
- Registration Number
- NCT00664248
- Locations
- 🇺🇸
Advanced Clinical Research - Jordan Valley, West Jordan, Utah, United States
🇺🇸International Dermatology Research, Inc., Miami, Florida, United States
🇺🇸The Nevada Center for Dermatology, Reno, Nevada, United States
Drug Development Updates
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