Gabapentin enacarbil (Horizant)

概览

Gabapentin enacarbil is a gabapentin prodrug used to treat Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).

作用机制

Although the exact mechanism of action of gabapentin in RLS and PHN is unknown, it is presumed to involve the descending noradrenergic system, resulting in the activation of spinal alpha2-adrenergic receptors.

适应症

For the treatment of adult Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN).

• Postherpetic Neuralgia
• Restless Legs Syndrome (RLS)