Artesunate

Generic Name
Artesunate
Brand Names
Artesunate Amivas
Drug Type
Small Molecule
Chemical Formula
C19H28O8
CAS Number
88495-63-0
Unique Ingredient Identifier
60W3249T9M
Background

Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin.

Artesunate was granted FDA approval on 26 May 2020.

Indication

Artesunate is indicated for the initial treatment of severe malaria in adult and pediatric patients.

Associated Conditions
Acute Uncomplicated Plasmodium Falciparum Malaria, Malaria, Cerebral, Severe Malaria
Associated Therapies
-

Safety and Efficacy Study of IV Artesunate to Treat Malaria

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-03-02
Last Posted Date
2019-10-01
Lead Sponsor
U.S. Army Medical Research and Development Command
Target Recruit Count
30
Registration Number
NCT00298610
Locations
🇰🇪

New Nyanza Provincial Hospital, Kisumu, New Nyanza, Kenya

Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women

Not Applicable
Completed
Conditions
First Posted Date
2006-02-06
Last Posted Date
2006-02-06
Lead Sponsor
University of North Carolina
Target Recruit Count
141
Registration Number
NCT00287300
Locations
🇲🇼

Mpemba and Madziabango Health Centers, Blantyre, Malawi

Artesunate in Preemptive Treatment of Human Cytomegalovirus (CMV) in Stem Cell Transplant Recipients

Phase 3
Completed
Conditions
First Posted Date
2006-02-01
Last Posted Date
2010-06-10
Lead Sponsor
Hadassah Medical Organization
Target Recruit Count
20
Registration Number
NCT00284687
Locations
🇮🇱

Hadassah Medical Organization, Jerusalem,, Israel

A Trial of Four Drug Regimens for the Prevention of Malaria in Senegalese Children

Phase 3
Completed
Conditions
First Posted Date
2005-08-22
Last Posted Date
2017-01-12
Lead Sponsor
London School of Hygiene and Tropical Medicine
Target Recruit Count
2200
Registration Number
NCT00132548
Locations
🇸🇳

Institut de recherche pour le developpement, Dakar, Senegal

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