MedPath

Elgemtumab

Generic Name
Elgemtumab
Drug Type
Biotech
CAS Number
1512559-37-3
Unique Ingredient Identifier
5F1CN52GFM
Background

Elgemtumab is under investigation in clinical trial NCT02167854 (Open-Label Study Evaluating the Safety and Tolerability of LJM716, BYL719 and Trastuzumab in Patients With Metastatic HER2+ Breast Cancer).

Open-Label Study Evaluating the Safety and Tolerability of LJM716, BYL719 and Trastuzumab in Patients With Metastatic HER2+ Breast Cancer

Phase 1
Completed
Conditions
Breast Cancer
Interventions
First Posted Date
2014-06-19
Last Posted Date
2021-07-09
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
23
Registration Number
NCT02167854
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Memorial Sloan Kettering at Basking Ridge, Basking Ridge, New Jersey, United States

๐Ÿ‡บ๐Ÿ‡ธ

Memorial Sloan Kettering Monmouth, Middletown, New Jersey, United States

๐Ÿ‡บ๐Ÿ‡ธ

Memorial Sloan Kettering Commack, Commack, New York, United States

and more 3 locations

Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC)

Phase 1
Completed
Conditions
Esophageal Squamous Cell Carcinoma
Interventions
First Posted Date
2013-04-02
Last Posted Date
2020-12-19
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
48
Registration Number
NCT01822613
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

Novartis Investigative Site, Manchester, United Kingdom

๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Medical Center Dept of Onc, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Karmanos Cancer Institute Dept of Onc, Detroit, Michigan, United States

and more 1 locations

Phase I Study LJM716 Combined With Trastuzumab in Patients With HER2 Overexpressing Metastatic Breast or Gastric Cancer

Phase 1
Completed
Conditions
Advanced HER2-positive Breast Cancer or Gastric Cancer
Interventions
First Posted Date
2012-05-21
Last Posted Date
2020-12-19
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
64
Registration Number
NCT01602406
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

Novartis Investigative Site, Oxford, United Kingdom

A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer

Phase 1
Completed
Conditions
HER2 + Gastric Cancer
Esophageal Squamous Cell Carcinoma
HER2 + Breast Cancer
HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma
Squamous Cell Carcinoma of Head and Neck
Interventions
First Posted Date
2012-05-15
Last Posted Date
2020-12-19
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
54
Registration Number
NCT01598077
Locations
๐Ÿ‡จ๐Ÿ‡ณ

Novartis Investigative Site, Taipei, Taiwan

๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Medical Center University of Chicago (16), Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Massachusetts General Hospital SC-5, Boston, Massachusetts, United States

and more 2 locations
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