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APR-548

Generic Name
APR-548
Drug Type
Small Molecule
Background

APR-548 is an analog of eprenetapopt and a reactivator of mutant p53.

APR-548 in Combination With Azacitidine for the Treatment of TP53 Myelodysplastic Syndromes (MDS)

Phase 1
Terminated
Conditions
MDS
Myelodysplastic Syndromes
Interventions
First Posted Date
2020-11-20
Last Posted Date
2025-03-10
Lead Sponsor
Aprea Therapeutics
Target Recruit Count
4
Registration Number
NCT04638309
Locations
🇺🇸

Dana Farber Cancer Institue, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

and more 1 locations
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