MedPath

Peppermint oil

Generic Name
Peppermint oil
Drug Type
Biotech
CAS Number
8006-90-4
Unique Ingredient Identifier
AV092KU4JH

Overview

Extracted from the stem, leaves, and flowers of Mentha piperita L. plant, peppermint oil (Mentha piperita) is a popular essential oil used in aromatherapy for both external and internal use. Mentha piperita is a hybrid of spearmint (Mentha spicata) and water mint (Mentha aquatica) . Medicinal use of herbal ingredients such as peppermint oil has a long history of treating digestive disorders and upper respiratory symptoms and cough . There are various over-the-counter and commercial uses of peppermint oil due to its carminative, cholagogue, antibacterial, secretolytic, and choleretic actions . Peppermint oil contains pulegone, which is a naturally-occurring pesticide . Other active constituents of peppermint oil include Menthol, menthone, cineol, and several other volatile oils . Peppermint oil is used as a flavouring agent in foods and fragrance in hygienic or cosmetic products, and as an anti-itch and cooling agent in topical pharmaceutical products. It is also an active ingredient in topical analgesics for the relief of joint and muscle pain. Peppermint oil can be applied topically to temporarily relieve tension-type headache. The use of peppermint oil in the management of irritable bowel syndrome (IBS) has been investigated in many clinical studies due to its relaxing effects on smooth muscle; however the evidence supporting this use is unclear. Due to its effectiveness in relaxing GI smooth muscle but ability to induce gastroesophageal reflux, enteric-coated formulations of peppermint oil has been established which bypass the upper GI tract unmetabolized, thereby facilitating its effect in the lower GI tract without effects in the upper tract . Peppermint oil is safe and well-tolerated at commonly recommended dosage .

Indication

Indicated for the over-the-counter use for: -the symptomatic relief of minor spasms of the gastrointestinal tract, flatulence and abdominal pain, especially in patients with irritable bowel syndrome. -the temporary relief of itching associated with insect bites, eczema, minor burn, sunburn, minor skin irritations, minor cuts, scrapes, atopic dermatitis and other skin disorders. -the temporary symptomatic relief of mild joint and muscle pain as a local topical analgesic. -the temporary relief of tension-type headache.

Associated Conditions

  • Colic
  • Cough
  • Flatulence
  • Hypertonicity of the small intestine
  • Irritable Bowel Syndrome (IBS)
  • Mild pain
  • Myalgia
  • Nasal Congestion
  • Gas pain

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
BIO EARTH MANUFACTURING (PTY) LTD
70116-025
TOPICAL
0.8 g in 100 mL
5/28/2025

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
COLPERMIN CAPSULE 187mg
SIN13034P
CAPSULE, ENTERIC COATED
187mg
11/4/2004

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
RICOLA SWISS HERB COUGH DROPORANGE MINT
ricola ltd.
01943766
Lozenge - Oral
0.7 MG
12/31/1993
SPIRIT OF PEPPERMINT LIQ 10%
jedmon products ltd.
00825719
Liquid - Oral
10 %
12/31/1990
PEPPERMINT SPIRIT
d.c. labs limited
00094870
Liquid - Oral ,  Topical
0.1 ML / ML
12/31/1951
NAUS-OVER
health 2000 inc.
02239662
Capsule - Oral
0.005 MG
N/A
COLPERMIN - SRC 187MG
reed & carnrick, division of block drug company (canada) ltd.
02178796
Capsule (Enteric-Coated) - Oral
187 MG / ECC
12/31/1995
HEM-RELIEF ONT
nature's way of canada ltd.
00656259
Ointment - Topical
0.5 %
12/31/1985
PEPPERMINT ESSENCE 10%
stanley pharmaceuticals, a division of vita health products inc.
00179744
Liquid - Oral
10 %
12/31/1965
SODA MINT TAB
stanley pharmaceuticals, a division of vita health products inc.
00179884
Tablet - Oral
0.003 ML
12/31/1957
AMOL
amol werke
00539732
Liquid - Oral
2.4 G / 100 G
10/10/1996
MENTHODYNE ONT
nature's way of canada ltd.
00656267
Ointment - Topical
4.1 %
12/31/1985

CIMA AEMPS Drug Approvals

Approved Product
Company
Registration Number
Pharmaceutical Form
Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product
Company
Registration Number
Dosage Form
Strength
Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name
MA Holder
MA Number
Pharmaceutical Form
Active Ingredient
Authorization Date
No UK EMC drug information found for this drug.

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