Enoxaparin sodium

Generic Name: Enoxaparin sodium

Brand Names: Lovenox, Inhixa

Drug Type: Small Molecule

Chemical Formula: -

CAS Number: 9005-49-6

Unique Ingredient Identifier: E47C0NF7LV

Background: Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated heparin, without increasing the risk of serious bleeding.

Indication: Enoxaparin is indicated for the prevention of ischemic complications in unstable angina and in non Q-wave myocardial infarction; it is indicated in conjunction with percutaneous intervention and/or other treatment for the management of acute ST elevation myocardial infarction.

Enoxaparin is also indicated in the prophylaxis of DVT in abdominal surgery, hip replacement, knee replacement, or medical patients with severely restricted mobility during acute illness. Additionally, enoxaparin is indicated for the inpatient treatment of DVT with or without pulmonary embolism and the treatment of outpatient DVT without pulmonary embolism.

Associated Conditions: Acute Coronary Syndrome (ACS), Acute Myocardial Infarction With ST Segment Elevation, Deep Vein Thrombosis, Ischemic complications caused by non-q wave myocardial infarction, Ischemic complications caused by unstable angina

Associated Therapies: Percutaneous Coronary Intervention (PCI)

Clinical Trials

Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation

Phase 3

Terminated

Conditions: Unstable Angina
Non ST Segment Elevation Myocardial Infarction

Interventions: Drug: Enoxaparin

First Posted Date: 2011-05-20

Last Posted Date: 2015-06-18

Lead Sponsor: Eurofarma Laboratorios S.A.

Target Recruit Count: 62

Registration Number: NCT01356992

Echo-Doppler Assessment of the Occurrence of Asymptomatic DVT in Orthopedic Replacement Surgery Under Enoxaparin

Phase 4

Completed

Conditions: Adverse Effect of Anticoagulants
Deep Vein Thrombosis
Venous Thrombosis

Interventions: Drug: Enoxaparin

First Posted Date: 2011-05-17

Last Posted Date: 2015-11-03

Lead Sponsor: Les Laboratoires des Médicaments Stériles

Target Recruit Count: 153

Registration Number: NCT01354704

Locations: 🇹🇳
Hospital Charle Nicolle, Tunis, Tunis BAB SOUIKA, Tunisia

Comparison of Subcutaneous Heparin and Enoxaparin for Deep Venous Thrombosis (DVT) Prophylaxis in Surgical Intensive Care Patients

Not Applicable

Withdrawn

Conditions: Lower Extremity Deep Venous Thrombosis

Interventions: Drug: enoxaparin
Drug: heparin

First Posted Date: 2011-03-30

Last Posted Date: 2013-05-20

Lead Sponsor: Lisa Louwers

Registration Number: NCT01325779

Locations: 🇺🇸
William Beaumont Hospital, Royal Oak, Michigan, United States

Two Weeks of Low Molecular Weight Heparin for Distal Vein Thrombosis

Phase 4

Conditions: Venous Thrombosis
Pulmonary Embolism

First Posted Date: 2010-12-03

Last Posted Date: 2010-12-06

Lead Sponsor: Monash Medical Centre

Target Recruit Count: 330

Registration Number: NCT01252420

Locations: 🇦🇺
Monash Medical Centre, Southern Health, Melbourne, Victoria, Australia
🇦🇺
Prince of Wales Hospital, Sydney, New South Wales, Australia
🇦🇺
Royal Adelaide Hospital, Adelaide, South Australia, Australia

and more 1 locations

BIBR 1048 Dose Range Finding Study in Prevention of Venous Thromboembolism in Patients With Primary Elective Total Hip or Knee Replacement Surgery

Phase 2

Completed

Conditions: Venous Thromboembolism

Interventions: Drug: BIBR 1048
Drug: Enoxaparin

First Posted Date: 2010-10-21

Last Posted Date: 2014-05-19

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 1973

Registration Number: NCT01225822

Locations: 🇦🇹
1160.19.43001 A.ö. Krankenhaus d. Statutarstadt Wiener Neustadt, Wr. Neustadt, Austria
🇨🇿
1160.19.42006 Hospital Mlada Boleslav, Mlada Boleslav, Czech Republic
🇧🇪
1160.19.32005 Virga Jesseziekenhuis, Gent, Belgium

and more 56 locations