Enoxaparin sodium

Generic Name
Enoxaparin sodium
Brand Names
Lovenox, Inhixa
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
9005-49-6
Unique Ingredient Identifier
E47C0NF7LV
Background

Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hosp...

Indication

Enoxaparin is indicated for the prevention of ischemic complications in unstable angina and in non Q-wave myocardial infarction; it is indicated in conjunction with percutaneous intervention and/or other treatment for the management of acute ST elevation myocardial infarction.
...

Associated Conditions
Acute Coronary Syndrome (ACS), Acute Myocardial Infarction With ST Segment Elevation, Deep Vein Thrombosis, Ischemic complications caused by non-q wave myocardial infarction, Ischemic complications caused by unstable angina
Associated Therapies
Percutaneous Coronary Intervention (PCI)

Nebulized Heparin in Severe Acute Respiratory Syndrome COVID-19

First Posted Date
2020-08-28
Last Posted Date
2020-08-31
Lead Sponsor
Clinica San Camilo, Argentina
Target Recruit Count
200
Registration Number
NCT04530578
Locations
🇦🇷

Clinica San Camilo, Ciudad Autonoma de Buenos Aire, Buenos Aires, Argentina

Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection

First Posted Date
2020-08-27
Last Posted Date
2021-05-06
Lead Sponsor
Massimo Girardis
Target Recruit Count
210
Registration Number
NCT04528888
Locations
🇮🇹

ICU- University Hospital Modena, Modena, Italy

FREEDOM COVID-19 Anticoagulation Strategy

Phase 4
Completed
Conditions
Interventions
First Posted Date
2020-08-13
Last Posted Date
2023-03-16
Lead Sponsor
Valentin Fuster
Target Recruit Count
3460
Registration Number
NCT04512079
Locations
🇨🇴

Centro Médico Imbanaco, Cali, Colombia

🇨🇴

Clínica Shaio, Bogotá, Colombia

🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

and more 18 locations

Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection

First Posted Date
2020-08-11
Last Posted Date
2020-08-11
Lead Sponsor
Hospital Regional de Alta especialidad de Ixtapaluca
Target Recruit Count
130
Registration Number
NCT04508439
Locations
🇲🇽

Hospital Regional de Alta Especialidad de Ixtapaluca, Mexico City, Ixtapaluca, Mexico

Early Prophylactic Low-molecular-weight Heparin (LMWH) in Symptomatic COVID-19 Positive Patients

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2020-07-30
Last Posted Date
2022-05-02
Lead Sponsor
Thrombosis Research Institute
Target Recruit Count
219
Registration Number
NCT04492254
Locations
🇦🇺

Harry Gibbs, National Co-ordinating Investigator, The Alfred Hospital, Melbourne, Australia

🇧🇪

Dr Frank Cools, National Co-ordinating Investigator, AZ Klina, Brasschaat, Belgium

🇿🇦

Prof. Barry Jacobson, National Coordinating Investigator, University of the Witwatersrand, Johannesburg, South Africa

Efficacy of Apixaban in Malignancy With Deep Venous Thrombosis

First Posted Date
2020-07-08
Last Posted Date
2020-07-08
Lead Sponsor
Beni-Suef University
Target Recruit Count
100
Registration Number
NCT04462003
Locations
🇪🇬

Faculty of Medicine,Beni-Suef University, Banī Suwayf, Beni-Suef, Egypt

Enoxaparin in COVID-19 Moderate to Severe Hospitalized Patients

First Posted Date
2020-06-11
Last Posted Date
2024-12-03
Lead Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Target Recruit Count
301
Registration Number
NCT04427098
Locations
🇮🇹

Fondazione Poliambulanza Chirurgia Vascolare, Brescia, Italy

🇮🇹

Piazzale Spedali Civili, 1, 25123 Brescia BS Medicina Interna UniBS 2° Medicina ASST Spedali Civili, Brescia, Italy

🇮🇹

Ospedale Morgagni Pierantoni U.O.C. Malattie Infettive, Forlì, Italy

and more 10 locations

High Versus Low LMWH Dosages in Hospitalized Patients With Severe COVID-19 Pneumonia and Coagulopathy

First Posted Date
2020-05-29
Last Posted Date
2020-05-29
Lead Sponsor
Azienda Ospedaliero-Universitaria di Modena
Target Recruit Count
300
Registration Number
NCT04408235
Locations
🇮🇹

Azienda Ospedaliero-Universitaria, Modena, Italy

Anticoagulation in Critically Ill Patients With COVID-19 (The IMPACT Trial)

First Posted Date
2020-05-28
Last Posted Date
2023-09-21
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
14
Registration Number
NCT04406389
Locations
🇺🇸

Weill Cornell Medicine, New York, New York, United States

🇺🇸

New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York, United States

Full Dose Heparin Vs. Prophylactic Or Intermediate Dose Heparin in High Risk COVID-19 Patients

First Posted Date
2020-05-26
Last Posted Date
2021-11-22
Lead Sponsor
Northwell Health
Target Recruit Count
257
Registration Number
NCT04401293
Locations
🇺🇸

Lenox Hill Hospital, New York, New York, United States

🇺🇸

Beth Israel Newark, Newark, New Jersey, United States

🇺🇸

Staten Island University Hospital, Staten Island, New York, United States

and more 3 locations
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