Sodium chloride

Generic Name: Sodium chloride

Brand Names: Amphenol-40, As 3, Bi-peglyte, Bicart, Bss, Bss Ophthalmic Solution, Cardioplegic, Citrasate, Clinimix E 2.75/5, Colyte, Corvatrol, Dextrose and Electrolyte No. 75, Dianeal, Dianeal Low Calcium 1.5, Dianeal Pd-2/1.5, Extraneal, Eye Stream, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hemosate Ultra, Hespan, Hizentra, Hyperlyte, Intersol, Isolyte S, Isolyte S pH 7.4, Isoplate, Lactate 1-2-3, Lactated Ringers, Menopur, Moviprep, Muro 128, Naturalyte, Normosol-M, Normosol-R, Nulytely, Nxstage Pureflow, P-Care M, P-Care MG, P-care, P-care X, Peglyte, Phoxillum, Physiolyte, Physioneal 40, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Plegisol, Plenvu, Prismasol, Procalamine 3, Ringers, Sag-M, Sclerodex, Suflave, Tis-U-sol

Drug Type: Small Molecule

Chemical Formula: ClNa

CAS Number: 7647-14-5

Unique Ingredient Identifier: 451W47IQ8X

Background: Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.

Indication: This intravenous solution is indicated for use in adults and pediatric patients as a source of electrolytes and water for hydration. Also, designed for use as a diluent and delivery system for intermittent intravenous administration of compatible drug additives.

Associated Conditions: Allergic Rhinitis (AR), Corneal Edema, Dehydration, Dehydration Hypertonic, Fluid Loss, Hemodilution, Hypokalemia, Hyponatremia, Hypotonic Dehydration, Hypovolaemia, Increase in Intracranial Pressure (ICP), Increased Intra Ocular Pressure (IOP), Inflammation of the Nasal Mucosa, Isotonic Dehydration, Metabolic Acidosis, Nasal Congestion, Nasal irritation, Oliguria caused by Acute Renal Failure (ARF), Potassium deficiency, Sinusitis, Skin Irritation, Sodium Depletion, Dryness of the nose, Hypochloremic state, Mild Metabolic acidosis, Mild, moderate Metabolic Acidosis

Associated Therapies: Electrolyte replacement, Fluid replacement therapy, Heart-Lung-Machine, Oral rehydration therapy, Parenteral Nutrition, Parenteral rehydration therapy, Peritoneal dialysis therapy, Plasma Volume Replacement, Regional Citrate Anticoagulation (RCA), Renal Replacement Therapies, Urine alkalinization therapy, Wound irrigation therapy, Ear wax removal, Fluid and electrolyte maintenance therapy, Increased renal excretion of toxic substances, Maintenance source of fluid and electrolytes, Parenteral drug administration, Reducing brain mass

Clinical Trials

The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance.

Not Applicable

Not yet recruiting

Conditions: Kidney Diseases

Interventions: Drug: Glucagon
Drug: Glucagon+Exendin9-39
Drug: Sodium chloride

First Posted Date: 2025-03-12

Last Posted Date: 2025-03-12

Lead Sponsor: Bispebjerg Hospital

Target Recruit Count: 10

Registration Number: NCT06872060

Use of Desmopressin Prior to Graft Kidney Biopsy in Patients with High Risk of Bleeding

Phase 4

Conditions: Bleeding
Transplant, Kidney
Desmopressin
Kidney Biopsy

Interventions: Drug: Sodium Chloride
Drug: Desmopressin (DDAVP)

First Posted Date: 2024-10-02

Last Posted Date: 2024-10-02

Lead Sponsor: Hospital de Clinicas de Porto Alegre

Target Recruit Count: 96

Registration Number: NCT06622187

Locations: 🇧🇷
Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil

Role of IV Calcium to Prevent Diltiazem-related Hypotension

Phase 4

Completed

Conditions: Hypotension Drug-Induced
Atrial Fibrillation
Rapid Ventricular Response

Interventions: Drug: 90 mg of calcium
Drug: 180 mg Calcium
Drug: Sodium chloride

First Posted Date: 2024-07-10

Last Posted Date: 2024-07-11

Lead Sponsor: Haseki Training and Research Hospital

Target Recruit Count: 217

Registration Number: NCT06494007

Locations: 🇹🇷
Haseki Training and Research Hospital, Istanbul, Fatih, Turkey

Metreleptin in Anorexia Nervosa

Phase 2

Recruiting

Conditions: Anorexia Nervosa

Interventions: Drug: Sodium chloride

First Posted Date: 2024-03-12

Last Posted Date: 2025-05-14

Lead Sponsor: Gabriella Milos

Target Recruit Count: 50

Registration Number: NCT06305182

Locations: 🇨🇭
Eating Disorder Unit, Clinic of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland

NAPO - Novel Approach for Oligospermia

Phase 1

Active, not recruiting

Conditions: Infertility, Male

Interventions: Drug: Denosumab
Drug: sodium chloride

First Posted Date: 2024-03-08

Last Posted Date: 2025-02-13

Lead Sponsor: Martin Blomberg Jensen

Target Recruit Count: 42

Registration Number: NCT06300229

Locations: 🇩🇰
Division of Translational Endocrinology, Department of Endocrinology and Internal Medicine, Copenhagen, Denmark

Impact of Postoperative Skin Disinfection With Chlorhexidine on Bacterial Colonization

Phase 4

Completed

Conditions: Surgical Site Infection

Interventions: Drug: Sodium Chloride

First Posted Date: 2023-11-02

Last Posted Date: 2023-11-02

Lead Sponsor: Linkoeping University

Target Recruit Count: 60

Registration Number: NCT06114459

Locations: 🇸🇪
Ryhov Hospital, Jönköping, Småland, Sweden

Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell Arteritis

Phase 2

Active, not recruiting

Conditions: Giant Cell Arteritis

Interventions: Drug: Methotrexate
Drug: Sodium chloride

First Posted Date: 2022-11-21

Last Posted Date: 2024-04-10

Lead Sponsor: University of Bonn

Target Recruit Count: 52

Registration Number: NCT05623592

Locations: 🇩🇪
Medical Clinic and Polyclinic III Internal medicine Oncology, Hematology University Hospital Bonn, Rheumatology and Clinical Immunology, Bonn, Germany

A Phase 1, Randomised, Double-blinded, Placebo-controlled, Dose-escalation Study to Evaluate the Safety and Immunogenicity of RH109 as Booster

Phase 1

Withdrawn

Conditions: COVID-19 Pandemic

Interventions: Biological: Lyophilized COVID-19 mRNA Vaccine
Drug: Sodium chloride

First Posted Date: 2022-11-08

Last Posted Date: 2023-07-14

Lead Sponsor: Wuhan Rhegen Biotechnology Co., Ltd.

Registration Number: NCT05609045

Bronchiectasis Alpha-1 Augmentation Trial- Modulating Airway Neutrophil Function

Phase 4

Recruiting

Conditions: Bronchiectasis Adult

Interventions: Drug: Alpha 1-Proteinase Inhibitor 180mg/kg
Drug: Alpha 1-Proteinase Inhibitor 120mg/kg
Drug: Sodium chloride

First Posted Date: 2022-10-17

Last Posted Date: 2023-04-14

Lead Sponsor: University of Dundee

Target Recruit Count: 20

Registration Number: NCT05582798

Locations: 🇬🇧
NHS Tayside, Dundee, United Kingdom

Bicarbonate for In-Hospital Cardiac Arrest

Phase 4

Recruiting

Conditions: Cardiac Arrest

Interventions: Drug: Sodium bicarbonate
Drug: Sodium chloride

First Posted Date: 2022-10-03

Last Posted Date: 2025-01-30

Lead Sponsor: Lars Wiuff Andersen

Target Recruit Count: 778

Registration Number: NCT05564130

Locations: 🇩🇰
Nykøbing Falster Hospital, Nykøbing Falster, Denmark
🇩🇰
Hospital of Southern Jutland - Aabenraa, Aabenraa, Denmark
🇩🇰
Copenhagen University Hospital - Herlev, Herlev, Denmark

and more 19 locations

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