Enoxaparin sodium

Generic Name
Enoxaparin sodium
Brand Names
Lovenox, Inhixa
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
9005-49-6
Unique Ingredient Identifier
E47C0NF7LV
Background

Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies. Enoxaparin markedly reduces the incidence of venous thromboembolism in hosp...

Indication

Enoxaparin is indicated for the prevention of ischemic complications in unstable angina and in non Q-wave myocardial infarction; it is indicated in conjunction with percutaneous intervention and/or other treatment for the management of acute ST elevation myocardial infarction.
...

Associated Conditions
Acute Coronary Syndrome (ACS), Acute Myocardial Infarction With ST Segment Elevation, Deep Vein Thrombosis, Ischemic complications caused by non-q wave myocardial infarction, Ischemic complications caused by unstable angina
Associated Therapies
Percutaneous Coronary Intervention (PCI)

Safety and Efficacy of Therapeutic Anticoagulation on Clinical Outcomes in Hospitalized Patients With COVID-19

First Posted Date
2020-05-07
Last Posted Date
2022-02-22
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
300
Registration Number
NCT04377997
Locations
🇺🇸

Abdurahman Khalil, Boston, Massachusetts, United States

Weight-Adjusted vs Fixed Low Doses of Low Molecular Weight Heparin For Venous Thromboembolism Prevention in COVID-19

First Posted Date
2020-05-04
Last Posted Date
2023-08-07
Lead Sponsor
Central Hospital, Nancy, France
Target Recruit Count
1000
Registration Number
NCT04373707
Locations
🇫🇷

Nancy Academic Hospital, Nancy, France

🇫🇷

Dijon Academic Hospital, Dijon, France

🇫🇷

Besançon Academic Hospital, Besançon, France

and more 14 locations

Comparison of Two Doses of Enoxaparin for Thromboprophylaxis in Hospitalized COVID-19 Patients

Phase 3
Completed
Conditions
Interventions
First Posted Date
2020-04-29
Last Posted Date
2021-06-08
Lead Sponsor
Niguarda Hospital
Target Recruit Count
189
Registration Number
NCT04366960
Locations
🇮🇹

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda, Milano, Italy

Preventing COVID-19 Complications With Low- and High-dose Anticoagulation

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2020-04-15
Last Posted Date
2021-09-14
Lead Sponsor
University Hospital, Geneva
Target Recruit Count
160
Registration Number
NCT04345848
Locations
🇨🇭

Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland

🇨🇭

Ospedale Regionale di Locarno, Locarno, Switzerland

🇨🇭

Hôpital du Valais, Sion, Switzerland

and more 1 locations

Impact of Prophylactic Low-molecular Weight Heparin Dosing on Clotting Parameters Following Cesarean Delivery

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2020-03-12
Last Posted Date
2022-01-28
Lead Sponsor
University of Utah
Target Recruit Count
146
Registration Number
NCT04305756
Locations
🇺🇸

University of Utah, Salt Lake City, Utah, United States

Comparison of Anticoagulation Prolongation vs. no Anticoagulation in STEMI Patients After Primary PCI

First Posted Date
2018-09-10
Last Posted Date
2023-05-03
Lead Sponsor
Beijing Anzhen Hospital
Target Recruit Count
2989
Registration Number
NCT03664180
Locations
🇨🇳

Beijing Anzhen Hospital, Capital Medical University, Beijing, China

Prolonged Enoxaparin in Primary Percutaneous Coronary Intervention

Phase 4
Completed
Conditions
Interventions
First Posted Date
2018-06-26
Last Posted Date
2022-11-15
Lead Sponsor
Sheffield Teaching Hospitals NHS Foundation Trust
Target Recruit Count
100
Registration Number
NCT03568838
Locations
🇬🇧

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, South Yorkshire, United Kingdom

Edoxaban for the Treatment of Coagulopathy in Patients With Active Cancer and Acute Ischemic Stroke: a Pilot Study. (ENCHASE Study)

First Posted Date
2018-06-26
Last Posted Date
2018-06-26
Lead Sponsor
Samsung Medical Center
Target Recruit Count
40
Registration Number
NCT03570281
Locations
🇰🇷

Department of Neurology, Samsung Medical Center, Seoul, Korea, Republic of

Pilot Study of Rosuvastatin and Enoxaparin Thromboprophylaxis Following Ovarian Cancer Surgery (O-STAT Study)

First Posted Date
2018-05-22
Last Posted Date
2023-06-15
Lead Sponsor
Beth Israel Deaconess Medical Center
Target Recruit Count
24
Registration Number
NCT03532139
Locations
🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Prevention of Thromboembolic Events in Total Knee Replacement Patients

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2018-01-08
Last Posted Date
2020-10-08
Lead Sponsor
Novartis Pharmaceuticals
Registration Number
NCT03393481
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