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Sulbactam

Generic Name
Sulbactam
Brand Names
Unasyn, Xacduro
Drug Type
Small Molecule
Chemical Formula
C8H11NO5S
CAS Number
68373-14-8
Unique Ingredient Identifier
S4TF6I2330

Overview

Sulbactam is a β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys antibiotic activity.

Background

Sulbactam is a β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys antibiotic activity.

Indication

Sulbactam is currently available in combination products with ampicillin. Within this formulation it is indicated for the treatment of infections due to susceptible strains of the designated microorganisms in the conditions listed below. Skin and Skin Structure Infections caused by beta-lactamase producing strains of Staphylococcus aureus, Escherichia coli, Klebsiella spp. (including K. pneumoniae), Proteus mirabilis, Bacteroides fragilis, Enterobacter spp., and Acinetobacter calcoaceticus. Intra-Abdominal Infections caused by beta-lactamase producing strains of Escherichia coli, Klebsiella spp. (including K. pneumoniae), Bacteroides spp. (including B. fragilis), and Enterobacter spp. Gynecological Infections caused by beta-lactamase producing strains of Escherichia coli, and Bacteroides spp. (including B. fragilis).

Associated Conditions

  • Animal bite
  • Bacterial Infections
  • Bacterial Infections caused by Beta lactamase producing bacteria
  • Bacterial Sinusitis
  • Bites, Human
  • Catheter Related Infections
  • Community Acquired Pneumonia (CAP)
  • Gynecological Infection
  • Infective Endocarditis (IE)
  • Intraabdominal Infections
  • Nosocomial Pneumonia
  • Postoperative Infections
  • Postoperative Wound Infection
  • Skin and Subcutaneous Tissue Bacterial Infections
  • Complicated Bacterial Infections caused by Beta lactamase producing bacteria
  • Moderate Bacterial Infections
  • Severe Bacterial Infections

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

UNASYN 750 FOR INJECTION
Manufacturer:Haupt Pharma Latina S.r.L
Form:INJECTION, POWDER, FOR SOLUTION
Strength:250 mg/vial
Online:Yes
Approved: 1988/06/23
Approval:SIN01950P
UNASYN 1500 FOR INJECTION
Manufacturer:Haupt Pharma Latina S.r.L
Form:INJECTION, POWDER, FOR SOLUTION
Strength:500 mg/vial
Online:Yes
Approved: 1988/06/23
Approval:SIN01948P
UNASYN 3000 FOR INJECTION
Manufacturer:Haupt Pharma Latina S.r.L
Form:INJECTION, POWDER, FOR SOLUTION
Strength:1 g/vial
Online:Yes
Approved: 1988/06/23
Approval:SIN01949P

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