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Pevonedistat

Generic Name
Pevonedistat
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C21H25N5O4S
CAS Number
905579-51-3
Unique Ingredient Identifier
S3AZD8D215
Background

Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.

Associated Conditions
-
Associated Therapies
-

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

Phase 1
Active, not recruiting
Conditions
Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia
Recurrent Acute Myeloid Leukemia
Secondary Acute Myeloid Leukemia
Therapy-Related Acute Myeloid Leukemia
Untreated Adult Acute Myeloid Leukemia
Interventions
Drug: Decitabine
Other: Laboratory Biomarker Analysis
Drug: Pevonedistat
Other: Pharmacological Study
First Posted Date
2017-01-04
Last Posted Date
2025-01-03
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
30
Registration Number
NCT03009240
Locations
🇺🇸

City of Hope Medical Center, Duarte, California, United States

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