Caffeine

Generic Name
Caffeine
Brand Names
Anacin, Arthriten Inflammatory Pain, Ascomp, Bc Arthritis, Bc Original Formula, Cafcit, Diurex, Dvorah, Esgic, Exaprin, Excedrin, Excedrin Tension Headache, Fioricet, Fioricet With Codeine, Fiorinal, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Midol Complete, Midol Cramps & Bodyaches, Migergot, Norgesic, Norgesic Forte, Orbivan, Orphengesic, Pamprin Max Formula, Peyona, Stanback Headache Powder Reformulated Jan 2011, Trezix, Trianal, Trianal C, Triatec, Triatec-8, Vanatol, Vanatol S, Vanquish, Vivarin, Peyona (previously Nymusa), Gencebok
Drug Type
Small Molecule
Chemical Formula
C8H10N4O2
CAS Number
58-08-2
Unique Ingredient Identifier
3G6A5W338E
Background

Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine. It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, whic...

Indication

Caffeine is indicated for the short term treatment of apnea of prematurity in infants and off label for the prevention and treatment of bronchopulmonary dysplasia caused by premature birth. In addition, it is indicated in combination with sodium benzoate to treat respiratory depression resulting from an overdose with CNS depressant drugs. Caffeine has a broa...

Associated Conditions
Acute Pain, Chronic Lung Disease of Prematurity, Common Cold, Dyspepsia, Fatigue, Fever, Flu caused by Influenza, Headache, Menstrual Pain, Myalgia, Pain, Pain caused by Rheumatism, Primary apnea of premature newborns, Respiratory Depression, Somnolence, Tension Headache, Toothache, Under-eyes Dark Circles, Vascular Headaches, Moderate Pain
Associated Therapies
Analgesia, Antacid therapy, Athletic Performance

EIMD Mechanisms Causing Force Loss

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2014-04-29
Last Posted Date
2017-06-05
Lead Sponsor
University of Oklahoma
Target Recruit Count
3
Registration Number
NCT02125643
Locations
🇺🇸

Sensory and Muscle Function Lab 7, Norman, Oklahoma, United States

The Effects of Caffeine on Pain-Based Pacing During a Cycling Time-Trial

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-04-16
Last Posted Date
2017-06-05
Lead Sponsor
University of Oklahoma
Target Recruit Count
15
Registration Number
NCT02115763
Locations
🇺🇸

University of Oklahoma Sensory and Muscle Function Lab, Norman, Oklahoma, United States

A Study of Caffeine on Cardiac Arrhythmias

First Posted Date
2014-03-24
Last Posted Date
2016-12-22
Lead Sponsor
Ottawa Heart Institute Research Corporation
Target Recruit Count
160
Registration Number
NCT02095405
Locations
🇨🇦

University of Ottawa Heart Institute, Ottawa, Ontario, Canada

Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity

First Posted Date
2014-01-29
Last Posted Date
2014-01-29
Lead Sponsor
Istituto Auxologico Italiano
Target Recruit Count
13
Registration Number
NCT02048215
Locations
🇮🇹

Istituto Auxologico Italiano -Ospedale San Giuseppe, Verbania, VB, Italy

Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain

First Posted Date
2013-08-27
Last Posted Date
2016-11-16
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
562
Registration Number
NCT01929031
Locations
🇺🇸

1335.1.202 Boehringer Ingelheim Investigational Site, Salt Lake City, Utah, United States

Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics

First Posted Date
2013-05-03
Last Posted Date
2014-04-21
Lead Sponsor
Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Target Recruit Count
117
Registration Number
NCT01845194
Locations
🇩🇪

Dept. of Clinical Pharmacology, Georg-August-University of Goettingen, Goettingen, Germany

Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players

First Posted Date
2013-04-18
Last Posted Date
2013-04-18
Lead Sponsor
K. Lieb
Target Recruit Count
40
Registration Number
NCT01834547
Locations
🇩🇪

Department of Psychiatry and Psychotherapy, Mainz, Germany

Caffein Consumption and Response Inhibition

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2013-03-20
Last Posted Date
2013-09-25
Lead Sponsor
Uppsala University
Target Recruit Count
21
Registration Number
NCT01815203
Locations
🇸🇪

Uppsala University, Uppsala, Sweden

Early Versus Routine Caffeine Administration in Extremely Preterm Neonates

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-02-05
Last Posted Date
2018-12-11
Lead Sponsor
Sharp HealthCare
Target Recruit Count
21
Registration Number
NCT01783561
Locations
🇺🇸

Sharp Memorial Hospital, San Diego, California, United States

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