Caffeine

Generic Name
Caffeine
Brand Names
Anacin, Arthriten Inflammatory Pain, Ascomp, Bc Arthritis, Bc Original Formula, Cafcit, Diurex, Dvorah, Esgic, Exaprin, Excedrin, Excedrin Tension Headache, Fioricet, Fioricet With Codeine, Fiorinal, Goody's Extra Strength, Goody's Headache Relief Shot, Goody's PM, Midol Complete, Midol Cramps & Bodyaches, Migergot, Norgesic, Norgesic Forte, Orbivan, Orphengesic, Pamprin Max Formula, Peyona, Stanback Headache Powder Reformulated Jan 2011, Trezix, Trianal, Trianal C, Triatec, Triatec-8, Vanatol, Vanatol S, Vanquish, Vivarin, Peyona (previously Nymusa), Gencebok
Drug Type
Small Molecule
Chemical Formula
C8H10N4O2
CAS Number
58-08-2
Unique Ingredient Identifier
3G6A5W338E
Background

Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine. It can be sourced from coffee beans, but also occurs naturally in various teas and cacao beans, whic...

Indication

Caffeine is indicated for the short term treatment of apnea of prematurity in infants and off label for the prevention and treatment of bronchopulmonary dysplasia caused by premature birth. In addition, it is indicated in combination with sodium benzoate to treat respiratory depression resulting from an overdose with CNS depressant drugs. Caffeine has a broa...

Associated Conditions
Acute Pain, Chronic Lung Disease of Prematurity, Common Cold, Dyspepsia, Fatigue, Fever, Flu caused by Influenza, Headache, Menstrual Pain, Myalgia, Pain, Pain caused by Rheumatism, Primary apnea of premature newborns, Respiratory Depression, Somnolence, Tension Headache, Toothache, Under-eyes Dark Circles, Vascular Headaches, Moderate Pain
Associated Therapies
Analgesia, Antacid therapy, Athletic Performance
Clinical Trials
Related News

The Influences of Caffeine on Heart Rate Variability of Preterm Infants

Completed
Conditions
Autonomic Nervous System
Interventions
Drug: Caffeine
First Posted Date
2013-01-16
Last Posted Date
2015-05-08
Lead Sponsor
Rambam Health Care Campus
Target Recruit Count
25
Registration Number
NCT01769118
Locations
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RMC, Haifa, Israel

Study to Evaluate Effect of Belatacept on Pharmacokinetics of Inje Cocktail in Healthy Volunteers

First Posted Date
2013-01-11
Last Posted Date
2014-06-27
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
45
Registration Number
NCT01766050
Locations
🇺🇸

Healthcare Discoveries, Llc D/B/A Icon Development Solutions, San Antonio, Texas, United States

Imaging the Effects of Zolpidem and Alprazolam in Healthy Volunteers at 3T

First Posted Date
2012-12-11
Last Posted Date
2012-12-11
Lead Sponsor
Mclean Hospital
Target Recruit Count
12
Registration Number
NCT01747590
Locations
🇺🇸

McLean Hospital, Belmont, Massachusetts, United States

Caffeine as a Therapy for Parkinson's Disease

Phase 3
Completed
Conditions
Parkinson's Disease
Interventions
Drug: Placebo
Drug: Caffeine
First Posted Date
2012-11-30
Last Posted Date
2017-03-22
Lead Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Target Recruit Count
119
Registration Number
NCT01738178
Locations
🇧🇷

Parana Parkinson Association - Pontifical Catholic University of Parana, Curitiba, PR, Brazil

🇨🇦

Movement Disorder Clinic - Deer Lodge Centre, Winnipeg, Manitoba, Canada

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The Ottawa Hospital - Civic Campus, Ottawa, Ontario, Canada

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The Effects of Caffeine on Vestibular Evoked Myogenic Potentials in Healthy Subjects

Phase 4
Conditions
Healthy Subjects
Interventions
Drug: Caffeine
First Posted Date
2012-09-26
Last Posted Date
2012-10-02
Lead Sponsor
Hospital do Servidor Publico Estadual
Target Recruit Count
25
Registration Number
NCT01693809
Locations
🇧🇷

Hospital do Servidor Publico Estadual, São Paulo, Brazil

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

First Posted Date
2012-07-10
Last Posted Date
2017-03-07
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
12
Registration Number
NCT01636557

Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

First Posted Date
2012-05-11
Last Posted Date
2020-12-21
Lead Sponsor
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Target Recruit Count
39
Registration Number
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Locations
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Comprehensive Cancer Centers, Las Vegas, Nevada, United States

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University of Kansas Cancer Center Medical Center, Kansas City, Kansas, United States

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Henry Ford Hospital Henry Ford, Detroit, Michigan, United States

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Development of Minidose Inje Cocktail Method for Simultaneous Evaluating Five Cytochrome P450 Isoforms in Human

First Posted Date
2012-04-04
Last Posted Date
2012-04-04
Lead Sponsor
Inje University
Target Recruit Count
26
Registration Number
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Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients

First Posted Date
2012-02-03
Last Posted Date
2016-06-10
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
72
Registration Number
NCT01525628
Locations
🇺🇸

1241.27.0006 Boehringer Ingelheim Investigational Site, La Mesa, California, United States

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1241.27.0003 Boehringer Ingelheim Investigational Site, Philadelphia, Pennsylvania, United States

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1241.27.0004 Boehringer Ingelheim Investigational Site, Marlton, New Jersey, United States

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Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digoxin in Cancer Subjects

First Posted Date
2012-01-25
Last Posted Date
2019-02-12
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
28
Registration Number
NCT01517399
Locations
🇺🇸

START - South Texas Accelerated Research Therapeutics, LLC, San Antonio, Texas, United States

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