Flurbiprofen
- Generic Name
- Flurbiprofen
- Drug Type
- Small Molecule
- Chemical Formula
- C15H13FO2
- CAS Number
- 5104-49-4
- Unique Ingredient Identifier
- 5GRO578KLP
- Background
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.
- Indication
Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis.
- Associated Conditions
- Ankylosing Spondylitis (AS), Back Pain, Acute, Chronic Back Pain, Menstrual Distress (Dysmenorrhea), Muscle Spasms, Non-Articular Rheumatic Muscle Spasms, Osteoarthritis (OA), Pain, Pain, Inflammatory, Post Traumatic Pain, Postoperative pain, Rheumatoid Arthritis, Spinal pain
KF2022#4-trial: Effects of a Beta Blocker and NSAID on CYP Mediated Drug Metabolism
- Conditions
- Drug Interaction
- Interventions
- First Posted Date
- 2024-08-22
- Last Posted Date
- 2024-08-22
- Lead Sponsor
- Helsinki University Central Hospital
- Target Recruit Count
- 12
- Registration Number
- NCT06566794
- Locations
- 🇫🇮
Department of Clinical Pharmacology, Helsinki, Finland
Electroencephalographic Characteristics of Chronic Pain in Patients With Spinal Cord Injury
- Conditions
- Chronic Pain
- Interventions
- Other: No interventionDrug: Esketamine(Continuous infusion)Device: Spinal Cord Stimulation
- First Posted Date
- 2024-08-01
- Last Posted Date
- 2024-08-13
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT06531837
- Locations
- 🇨🇳
Beijing Tiantan Hospital, Beijing, China
Flurbiprofen Tablet vs Spray In Oral Soft Tissue Wounds
- Conditions
- Drug UseOral Soft Tissue ConditionsDrug Effect
- Interventions
- First Posted Date
- 2024-02-02
- Last Posted Date
- 2024-07-26
- Lead Sponsor
- Yuzuncu Yıl University
- Target Recruit Count
- 40
- Registration Number
- NCT06238154
- Locations
- 🇹🇷
Yuzuncu Yil University, Van, Merkez, Turkey
Flurbiprofen Versus Aloe Vera Gel in the Treatment of Chronic Periodontitis in Smoking Patients.
- Conditions
- Periodontitis Chronic Generalized Severe
- Interventions
- First Posted Date
- 2023-09-18
- Last Posted Date
- 2023-09-18
- Lead Sponsor
- Beirut Arab University
- Target Recruit Count
- 60
- Registration Number
- NCT06041178
- Locations
- 🇱🇧
Beirut Arab University, Beirut, Lebanon
The Comparison of the Analgesic Effects of Dezocine and Sufentanil in Patient-controlled Analgesia After Laryngectomy
- Conditions
- Patient-controlled Analgesia
- Interventions
- First Posted Date
- 2023-08-21
- Last Posted Date
- 2023-08-21
- Lead Sponsor
- Eye & ENT Hospital of Fudan University
- Target Recruit Count
- 129
- Registration Number
- NCT06000137
- Locations
- 🇨🇳
Fudan University, Shanghai, Shanghai, China
Voxelotor CYP and Transporter Cocktail Interaction Study
- Conditions
- Sickle Cell Disease
- Interventions
- First Posted Date
- 2023-08-08
- Last Posted Date
- 2024-11-22
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 44
- Registration Number
- NCT05981365
- Locations
- 🇺🇸
ICON Early Phase Services, LLC, San Antonio, Texas, United States
Effect of Over-the-counter NSAIDS on Cough Reflex Sensitivity in Patients with Upper Respiratory Tract Infections
- Conditions
- CoughUpper Respiratory Tract Infections
- Interventions
- First Posted Date
- 2023-07-21
- Last Posted Date
- 2024-12-06
- Lead Sponsor
- University of Melbourne
- Target Recruit Count
- 101
- Registration Number
- NCT05955885
- Locations
- 🇦🇺
University of Melbourne, Carlton, Victoria, Australia
A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants
- Conditions
- Healthy Volunteers
- Interventions
- First Posted Date
- 2023-07-06
- Last Posted Date
- 2023-10-30
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 22
- Registration Number
- NCT05932277
- Locations
- 🇺🇸
ICON Lenexa, Lenexa, Kansas, United States
A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants
- Conditions
- Healthy Volunteers
- Interventions
- First Posted Date
- 2023-05-10
- Last Posted Date
- 2023-09-26
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 18
- Registration Number
- NCT05852769
- Locations
- 🇺🇸
ICON plc, Millcreek, Utah, United States
The Effects of NSAIDs on Bone Metabolism Following Exercise
- Conditions
- Bone ResorptionStress FractureBone Injury
- Interventions
- First Posted Date
- 2022-08-23
- Last Posted Date
- 2023-11-29
- Lead Sponsor
- United States Army Research Institute of Environmental Medicine
- Target Recruit Count
- 12
- Registration Number
- NCT05512013
- Locations
- 🇺🇸
United States Army Research Institute of Environmental Medicine, Natick, Massachusetts, United States
Drug Development Updates
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