Flurbiprofen
- Generic Name
- Flurbiprofen
- Drug Type
- Small Molecule
- Chemical Formula
- C15H13FO2
- CAS Number
- 5104-49-4
- Unique Ingredient Identifier
- 5GRO578KLP
- Background
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.
- Indication
Flurbiprofen tablets are indicated for the acute or long-term symptomatic treatment of rheumatoid arthritis, osteorarthritis and anklosing spondylitis. It may also be used to treat pain associated with dysmenorrhea and mild to moderate pain accompanied by inflammation (e.g. bursitis, tendonitis, soft tissue trauma). Topical ophthalmic formulations may be used pre-operatively to prevent intraoperative miosis.
- Associated Conditions
- Ankylosing Spondylitis (AS), Back Pain, Acute, Chronic Back Pain, Menstrual Distress (Dysmenorrhea), Muscle Spasms, Non-Articular Rheumatic Muscle Spasms, Osteoarthritis (OA), Pain, Pain, Inflammatory, Post Traumatic Pain, Postoperative pain, Rheumatoid Arthritis, Spinal pain
The Safety and Efficacy of 5% Lidocaine Patch and Flurbiprofen Patch for Relieving Acute Low Back Pain
- Conditions
- Acute Back Pain
- Interventions
- First Posted Date
- 2017-05-31
- Last Posted Date
- 2024-04-10
- Lead Sponsor
- Taipei Medical University Hospital
- Target Recruit Count
- 85
- Registration Number
- NCT03171987
- Locations
- 🇨🇳
Postal Hospital, Taipei, Taiwan
🇨🇳Taipei Medical University Hospital, Taipei, Taiwan
Oral Flurbiprofen Spray for Mucosal Graft Harvesting at the Palatal Area
- First Posted Date
- 2017-05-24
- Last Posted Date
- 2017-05-24
- Lead Sponsor
- Gazi University
- Target Recruit Count
- 48
- Registration Number
- NCT03165929
Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin
- Conditions
- Rheumatoid Arthritis
- Interventions
- First Posted Date
- 2017-04-27
- Last Posted Date
- 2017-12-15
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 26
- Registration Number
- NCT03131973
- Locations
- 🇺🇸
PPD Development, LP, Austin, Texas, United States
Microbiome Shift in Peri-mucositis by Anti-inflammatory Drugs
- Conditions
- Peri-implant Mucositis
- Interventions
- Drug: Placebo Oral Tablet
- First Posted Date
- 2017-03-24
- Last Posted Date
- 2017-03-31
- Lead Sponsor
- Polak David
- Target Recruit Count
- 100
- Registration Number
- NCT03090009
- Locations
- 🇮🇱
Hadassah Medical Organization, Jerusalem, Israel
Evaluation of the Effect of Appropriate Sedation for Patients After Gastrectomy: A Prospective Randomised Controlled Study
- Conditions
- Postoperative Sedation,Gastrectomy, Enhanced Recovery After Surgery
- Interventions
- First Posted Date
- 2016-02-04
- Last Posted Date
- 2016-02-04
- Lead Sponsor
- Chinese Medical Association
- Target Recruit Count
- 80
- Registration Number
- NCT02674737
- Locations
- 🇨🇳
Institute of General Surgery of Jinling Hospital, Nanjing, Jiangsu, China
Evaluation of the Effect of Appropriate Sedation for Patients After Abdominal Surgeries : A Prospective Randomised Controlled Study
- Conditions
- Postoperative Sedation, Abdominal Surgery
- Interventions
- First Posted Date
- 2016-02-02
- Last Posted Date
- 2016-02-02
- Lead Sponsor
- Chinese Medical Association
- Target Recruit Count
- 154
- Registration Number
- NCT02670954
- Locations
- 🇨🇳
Institute of General Surgery of Jinling Hospital, Nanjing, Jiangsu, China
Effect of Parecoxib Sodium and Flurbiprofen Injection on Postoperative Shivering
- Conditions
- Postoperative Shivering
- Interventions
- First Posted Date
- 2015-10-07
- Last Posted Date
- 2015-10-27
- Lead Sponsor
- Guangxi Medical University
- Target Recruit Count
- 166
- Registration Number
- NCT02569905
- Locations
- 🇨🇳
Anesthesia Department, Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China
Prospective Analgesic Compound Efficacy (PACE) Study
- Conditions
- RadiculopathyGoutMuscle SpasmsHeadacheArthritisSynovitisMigraineTendonitis
- First Posted Date
- 2015-03-31
- Last Posted Date
- 2018-02-01
- Lead Sponsor
- Express Specialty Pharmacy
- Target Recruit Count
- 300
- Registration Number
- NCT02403687
A Phase 1 Drug-drug Interaction Study in Healthy Volunteers
- Conditions
- Drug-drug Interaction Study
- Interventions
- First Posted Date
- 2014-08-27
- Last Posted Date
- 2014-11-18
- Lead Sponsor
- Bristol-Myers Squibb
- Target Recruit Count
- 20
- Registration Number
- NCT02227173
- Locations
- 🇺🇸
Healthcare Discoveries, LLC d/b/a ICON Development Solutions, San Antonio, Texas, United States
Comparison of Two Kinds of Postoperative Analgesia After Amputation
- Conditions
- ComplicationsPain
- Interventions
- First Posted Date
- 2014-04-15
- Last Posted Date
- 2015-03-12
- Lead Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
- Target Recruit Count
- 36
- Registration Number
- NCT02114463
- Locations
- 🇨🇳
Guangzhou Military Region General Hospital, Department of Anesthesiology, Guangzhou, Guangdong, China
Drug Development Updates
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