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Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis or necrotic heart tissue .
Stannous chloride is used as a source of tin in radiopharmaceutical kits. Tin reduces technetium-99m, the active radiological agent, allowing it to form a complex with phosphate-containing moeities . These complexes localize primarily in bone (40-50%) and infracted myocardium (0.01-0.02%/g of tissue) allowing for imaging of areas of altered osteogenesis or necrotic heart tissue .
Stannous chloride acts as a reducing agent for technetium-99m allowing formation of a Tc99m-Sn-pyrophosphate complex in combination sodium pyrophosphate . See Technetium Tc-99m pyrophosphate for information on the active agent.
Stannous chloride is a component of technetium-99m agents indicated for imaging of the skeleton for areas of altered osteogenesis or in the detection of infarcted heart tissue .
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