Amlodipine
- Generic Name
- Amlodipine
- Brand Names
- Amlobenz, Azor, Caduet, Dafiro, Exforge, Exforge Hct, Katerzia, Lotrel, Norliqva, Norvasc, Prestalia, Tribenzor, Twynsta, Viacoram
- Drug Type
- Small Molecule
- Chemical Formula
- C20H25ClN2O5
- CAS Number
- 88150-42-9
- Unique Ingredient Identifier
- 1J444QC288
- Background
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnorma...
- Indication
Amlodipine may be used alone or in combination with other antihypertensive and antianginal agents for the treatment of the following conditions :
• Hypertension
• Coronary artery disease
• Chronic stable angina
• Vasospastic angina (Prinzmetal’s or Variant angina)
...
- Associated Conditions
- Cardiovascular Events, Chronic Stable Angina Pectoris, Coronary Artery Disease (CAD), Homozygous Familial Hypercholesterolaemia (HoFH), Hypertension, Hypertension, Essential Hypertension, Mixed Dyslipidemias, Primary Hypercholesterolemia, Vasospastic Angina
- Associated Therapies
- -
Personalised Electronic Record Supported Optimisation of Amlodipine for Patients With Hypertension
- First Posted Date
- 2024-12-03
- Last Posted Date
- 2024-12-03
- Lead Sponsor
- Queen Mary University of London
- Registration Number
- NCT06713785
Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries
- Conditions
- Interventions
- First Posted Date
- 2024-05-22
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 150
- Registration Number
- NCT06424834
- Locations
- 🇺🇸
Stanford Hospital, Palo Alto, California, United States
A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial)
- Conditions
- Interventions
- First Posted Date
- 2023-11-29
- Last Posted Date
- 2024-07-29
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 120
- Registration Number
- NCT06150560
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Skin Sodium and Salt Sensitivity of Blood Pressure
- Conditions
- Interventions
- First Posted Date
- 2023-08-04
- Last Posted Date
- 2023-08-04
- Target Recruit Count
- 60
- Registration Number
- NCT05976438
- Locations
- 🇬🇧
Addenbrooke's Hospital, Cambridge, United Kingdom
🇬🇧St Thomas' Hospital, London, United Kingdom
Multi-Omics to Predict the Blood Pressure Response to Antihypertensives
- Conditions
- Interventions
- First Posted Date
- 2023-06-23
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 96
- Registration Number
- NCT05917275
- Locations
- 🇳🇱
Radboudumc, Nijmegen, Netherlands
Pharmacokinetics of Irbesartan High/Amlodipine FDC and Co-administration of Irbesartan High and Amlodipine in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2023-01-18
- Last Posted Date
- 2023-08-18
- Lead Sponsor
- Handok Inc.
- Target Recruit Count
- 44
- Registration Number
- NCT05688085
- Locations
- 🇰🇷
H Plus Yangji Hospital, Seoul, Korea, Republic of
Pharmacokinetics of Irbesartan/Amlodipine FDC and Co-administration of Irbesartan and Amlodipine in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2022-12-23
- Last Posted Date
- 2023-08-18
- Lead Sponsor
- Handok Inc.
- Target Recruit Count
- 46
- Registration Number
- NCT05663073
- Locations
- 🇰🇷
H Plus Yangji Hospital, Seoul, Korea, Republic of
Effectiveness and Safety of Combination of Nebivolol and Amlodipine in Hypertensive Patients Versus Each Monotherapy
- First Posted Date
- 2022-08-24
- Last Posted Date
- 2023-03-01
- Lead Sponsor
- Menarini International Operations Luxembourg SA
- Target Recruit Count
- 291
- Registration Number
- NCT05513937
- Locations
- 🇧🇬
Medical Center Hera EOOD, Sofia, Bulgaria
Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patients
- Conditions
- Interventions
- First Posted Date
- 2022-07-20
- Last Posted Date
- 2022-07-20
- Lead Sponsor
- Ayub Teaching Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT05467384
Effects and Safety of Clonidine Patch on Young and Middle-aged Smokers With Mild Hypertension
- Conditions
- Interventions
- First Posted Date
- 2022-06-13
- Last Posted Date
- 2024-01-17
- Lead Sponsor
- Jing Liu
- Target Recruit Count
- 92
- Registration Number
- NCT05416840
- Locations
- 🇨🇳
Peking University People's Hospital, Beijing, China
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.