Nitisinone
- Generic Name
- Nitisinone
- Brand Names
- Nityr, Orfadin
- Drug Type
- Small Molecule
- Chemical Formula
- C14H10F3NO5
- CAS Number
- 104206-65-7
- Unique Ingredient Identifier
- K5BN214699
Overview
Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin.
Background
Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin.
Indication
Used as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1.
Associated Conditions
- Tyrosinemia Type 1
Clinical Trials
FDA Approved Products
Nitisinone
Manufacturer:Torrent pharmaceuticals limited
Route:oral
Strength:2 mg in 1 1
Approved: 2023/01/10
NDC:13668-629
Orfadin
Manufacturer:SWEDISH ORPHAN BIOVITRUM AB (PUBL)
Route:ORAL
Strength:10 mg in 1 1
Approved: 2016/06/20
NDC:66658-110
Nitisinone
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:2 mg in 1 1
Approved: 2019/11/12
NDC:63629-2234
NITYR
Manufacturer:Cycle Pharmaceuticals Ltd.
Route:ORAL
Strength:5 mg in 1 1
Approved: 2018/11/14
NDC:70709-005
Nitisinone
Manufacturer:Torrent pharmaceuticals limited
Route:oral
Strength:20 mg in 1 1
Approved: 2023/01/10
NDC:13668-632
Singapore Approved Products
No Singapore products found for this drug
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