Citalopram
- Generic Name
- Citalopram
- Brand Names
- Celexa, Ctp
- Drug Type
- Small Molecule
- Chemical Formula
- C20H21FN2O
- CAS Number
- 59729-33-8
- Unique Ingredient Identifier
- 0DHU5B8D6V
- Background
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. Citalopram enhances serotonergic transmission through the i...
- Indication
Citalopram is approved by the FDA for treating adults with major depressive disorder. It has also been used off-label to treat various diseases, including but not limited to sexual dysfunction, ethanol abuse, psychiatric conditions such as obsessive-compulsive disorder (OCD), social anxiety disorder, panic disorder, and diabetic neuropathy.
- Associated Conditions
- Alcohol Abuse, Anorexia Nervosa (AN), Binge Eating Disorder (BED), Bulimia Nervosa, Depression, Diabetic Neuropathies, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Separation Anxiety Disorder, Social Anxiety Disorder (SAD)
- Associated Therapies
- -
Treatment of Adolescent Suicide Attempters (TASA)
- Conditions
- First Posted Date
- 2004-03-26
- Last Posted Date
- 2020-06-22
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 120
- Registration Number
- NCT00080158
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸Columbia University at the New York State Psychiatric Institute, New York, New York, United States
🇺🇸New York University Child Study Center, New York, New York, United States
Treating Behavioral Disturbances in Individuals With Dementia
- Conditions
- First Posted Date
- 2003-12-03
- Last Posted Date
- 2014-03-10
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 137
- Registration Number
- NCT00073658
- Locations
- 🇺🇸
University of Pittsburgh Medical Center/Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, United States
PUFA Augmentation in Treatment of Major Depression
- Conditions
- First Posted Date
- 2003-08-15
- Last Posted Date
- 2008-01-25
- Target Recruit Count
- 60
- Registration Number
- NCT00067301
- Locations
- 🇺🇸
Cedars-Sinai Medical Center Dept. of Psychiatry, Los Angeles, California, United States
Drug Therapy to Treat Minor Depression
- Conditions
- Interventions
- First Posted Date
- 2002-11-13
- Last Posted Date
- 2018-05-11
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 73
- Registration Number
- NCT00048815
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
🇺🇸University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, United States
🇺🇸Massachusetts General Hospital, Boston, Massachusetts, United States
Ethnic Variations in Antidepressant Response
- First Posted Date
- 2002-10-16
- Last Posted Date
- 2009-08-04
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 400
- Registration Number
- NCT00047671
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Department of Psychiatry, Clinical Trials Unit, Los Angeles, California, United States
🇺🇸Harbor-UCLA Medical Center, Torrance, California, United States
🇺🇸UCLA/King-Drew, Los Angeles, California, United States
Magnetic Stimulation Therapy for Treating Vascular Depression
- Conditions
- Interventions
- First Posted Date
- 2002-09-06
- Last Posted Date
- 2013-09-27
- Lead Sponsor
- University of Iowa
- Target Recruit Count
- 132
- Registration Number
- NCT00044798
- Locations
- 🇺🇸
University of Iowa Health Care, Iowa City, Iowa, United States
Sequenced Treatment Alternatives to Relieve Depression (STAR*D)
- Conditions
- First Posted Date
- 2001-07-23
- Last Posted Date
- 2009-09-25
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 4000
- Registration Number
- NCT00021528
- Locations
- 🇺🇸
Harbor UCLA Family Health Care Center, Harbor City, California, United States
🇺🇸UCLA General Outpatient Psychiatry Clinic, Los Angeles, California, United States
🇺🇸UCLA Internal Medicine Clinic, Los Angeles, California, United States
Treatment of SSRI-Resistant Depression In Adolescents (TORDIA)
- Conditions
- Interventions
- First Posted Date
- 2001-07-12
- Last Posted Date
- 2014-03-12
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 334
- Registration Number
- NCT00018902
- Locations
- 🇺🇸
Kaiser Permanente Center for Health Research, Portland, Oregon, United States
🇺🇸University of California at Los Angeles, Los Angeles, California, United States
🇺🇸Brown University, Providence, Rhode Island, United States
CATIE-Alzheimer's Disease Trial
- Conditions
- First Posted Date
- 2001-04-23
- Last Posted Date
- 2015-06-17
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 450
- Registration Number
- NCT00015548
- Locations
- 🇺🇸
VA Medical Center, Coatesville, Pennsylvania, United States
🇺🇸University of California, Irvine Medical Center, Irvine, California, United States
🇺🇸Louisiana State University Health Sciences Center, Shreveport, Louisiana, United States
Drug Development Updates
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