Citalopram

Generic Name
Citalopram
Brand Names
Celexa, Ctp
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
59729-33-8
Unique Ingredient Identifier
0DHU5B8D6V
Background

Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. Citalopram enhances serotonergic transmission through the i...

Indication

Citalopram is approved by the FDA for treating adults with major depressive disorder. It has also been used off-label to treat various diseases, including but not limited to sexual dysfunction, ethanol abuse, psychiatric conditions such as obsessive-compulsive disorder (OCD), social anxiety disorder, panic disorder, and diabetic neuropathy.

Associated Conditions
Alcohol Abuse, Anorexia Nervosa (AN), Binge Eating Disorder (BED), Bulimia Nervosa, Depression, Diabetic Neuropathies, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD), Panic Disorder, Post Traumatic Stress Disorder (PTSD), Premature Ejaculation, Premenstrual Dysphoric Disorder (PMDD), Separation Anxiety Disorder, Social Anxiety Disorder (SAD)
Associated Therapies
-

Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD)

First Posted Date
2011-03-11
Last Posted Date
2022-04-07
Lead Sponsor
PharmaNeuroBoost N.V.
Target Recruit Count
555
Registration Number
NCT01312922
Locations
🇺🇸

Site 108, Winter Park, Florida, United States

🇺🇸

Site 133, Atlanta, Georgia, United States

🇺🇸

Site 110, Baltimore, Maryland, United States

and more 28 locations

Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms

First Posted Date
2010-08-27
Last Posted Date
2011-08-24
Lead Sponsor
Columbia Northwest Pharmaceuticals
Target Recruit Count
80
Registration Number
NCT01189812
Locations
🇺🇸

Artemis Institute for Clinical Research, San Diego, California, United States

🇺🇸

Northwest Clinical Research Center, Bellevue, Washington, United States

A Study of Medication With or Without Psychotherapy for Complicated Grief

First Posted Date
2010-08-11
Last Posted Date
2017-01-24
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
395
Registration Number
NCT01179568
Locations
🇺🇸

VASDHS / University of California San Diego, San Diego, California, United States

🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

New York State Psychiatric Institute, New York, New York, United States

and more 1 locations

Pain Inhibition in Patients With Rheumatoid Arthritis and Central Sensitivity Syndromes

First Posted Date
2010-07-01
Last Posted Date
2010-07-01
Lead Sponsor
Vrije Universiteit Brussel
Target Recruit Count
70
Registration Number
NCT01154647
Locations
🇧🇪

University Hospital Antwerp, Edegem, Antwerp, Belgium

Study of Treatment of Depression in Refractory Asthma

Not Applicable
Conditions
Interventions
First Posted Date
2010-06-30
Last Posted Date
2012-02-03
Lead Sponsor
Liam Heaney
Target Recruit Count
40
Registration Number
NCT01153165
Locations
🇬🇧

Regional Respiratory Centre, Belfast City Hospital, Belfast, United Kingdom

Antidepressants to Promote Recovery of Cardiac Patients Suffering From Depression

First Posted Date
2010-04-07
Last Posted Date
2016-01-28
Lead Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Target Recruit Count
7
Registration Number
NCT01099592
Locations
🇨🇦

Montreal Heart Insitute, Montreal, Quebec, Canada

🇨🇦

Centre de recherche du CHUM, Montreal, Quebec, Canada

DECIFER: Depression and Citalopram In First Episode Recovery

First Posted Date
2009-12-31
Last Posted Date
2019-12-17
Lead Sponsor
NYU Langone Health
Target Recruit Count
95
Registration Number
NCT01041274
Locations
🇺🇸

New York University Langone Medical Center/ Bellevue Hospital, New York, New York, United States

Antidepressant Controlled Trial for Negative Symptoms in Schizophrenia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-12-15
Last Posted Date
2024-03-28
Lead Sponsor
Imperial College London
Target Recruit Count
62
Registration Number
NCT01032083
Locations
🇬🇧

Avon and Wiltshire mental health partnership, Bristol, United Kingdom

🇬🇧

Lincolnshire partnership NHS foundation trust, Lincoln, United Kingdom

🇬🇧

Manchester health and social care trust, Manchester, United Kingdom

and more 11 locations

Cognitive Flexibility in Major Depression in the Course of Pharmacological and Psychotherapeutic Treatment

First Posted Date
2009-10-14
Last Posted Date
2009-10-14
Lead Sponsor
Zentrum für Integrative Psychiatrie
Target Recruit Count
45
Registration Number
NCT00993876
Locations
🇩🇪

Zentrum für Integrative Psychiatrie, Kiel, Germany

N-methylglycine (Sarcosine) Treatment for Depression

First Posted Date
2009-09-15
Last Posted Date
2011-07-12
Lead Sponsor
China Medical University Hospital
Target Recruit Count
40
Registration Number
NCT00977353
Locations
🇨🇳

Department of Psychiatry, China Medical University Hospital, Taichung, Taiwan

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