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Aldosterone

Generic Name
Aldosterone
Drug Type
Small Molecule
Chemical Formula
C21H28O5
CAS Number
52-39-1
Unique Ingredient Identifier
4964P6T9RB
Background

A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

Clinical Trials
Related News

Investigating Salt Taste Threshold in Patients Being Investigated for Primary Hyperaldosteronism Before and After Treatment.

Withdrawn
Conditions
Salt; Excess
Hypertension
Hyperaldosteronism; Primary
Appetite Disorders
Interventions
Procedure: adrenalectomy
First Posted Date
2020-09-21
Last Posted Date
2024-05-10
Lead Sponsor
Imperial College London
Registration Number
NCT04556279
Locations
🇬🇧

Imperial College Healthcare NHS Trust, London, United Kingdom

Non Invasive Assessment of Heart Failure

Early Phase 1
Conditions
Heart Failure
Interventions
First Posted Date
2019-09-06
Last Posted Date
2020-01-09
Lead Sponsor
Assiut University
Target Recruit Count
100
Registration Number
NCT04078425

Controlling Blood Pressure in Treatment Resistant Hypertension: A Pilot Study

Not Applicable
Completed
Conditions
Hypertension
Interventions
Drug: Renin treatment-guided Therapeutics
Other: Referral Hypertension specialist
First Posted Date
2014-06-19
Last Posted Date
2018-07-23
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
70
Registration Number
NCT02167464
Locations
🇺🇸

AnMed, Anderson, South Carolina, United States

🇺🇸

Beaufort Jasper Hampton Comprehensive Health, Beaufort, South Carolina, United States

🇺🇸

Carolina Medical Affiliates, Spartanburg, South Carolina, United States

and more 5 locations

Aldosterone and Glucose Homeostasis

Not Applicable
Completed
Conditions
Diabetes Mellitus
Interventions
Drug: Vehicle Infusion (V)
Other: High Sodium Diet (HS)
Other: Low Sodium Diet (LS)
First Posted Date
2008-08-11
Last Posted Date
2017-04-06
Lead Sponsor
Vanderbilt University
Target Recruit Count
34
Registration Number
NCT00732160
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Studies on Aldosterone and Vascular Function

Phase 1
Completed
Conditions
Inflammation
Interventions
Dietary Supplement: low or high sodium diet
Drug: placebo
First Posted Date
2008-06-18
Last Posted Date
2008-06-18
Lead Sponsor
Yale University
Target Recruit Count
20
Registration Number
NCT00700479
Locations
🇺🇸

Yale University School of Medicine, New Haven, Connecticut, United States

Curing Atrial Fibrillation in Heart Failure

Not Applicable
Completed
Conditions
Chronic Heart Failure
Atrial Fibrillation
Interventions
Drug: ACE inhibitor - ramipril, enalapril, captopril, perindopril, lisinopril
Procedure: radiofrequency ablation
Drug: Beta Blocker (BB) - metoprolol, bisoprolol, carvedilol
First Posted Date
2006-02-15
Last Posted Date
2012-06-01
Lead Sponsor
NHS Greater Glasgow and Clyde
Target Recruit Count
41
Registration Number
NCT00292162
Locations
🇬🇧

Glasgow Royal Infirmary, Glasgow, Scotland, United Kingdom

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