Pantoprazole

Generic Name: Pantoprazole

Brand Names: Protonix, Somac Control, Tecta, Pantozol Control, Controloc Control

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₅F_₂N_₃O_₄S

CAS Number: 102625-70-7

Unique Ingredient Identifier: D8TST4O562

Background: Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...

Indication: Pantoprazole Injection:

Treatment of gastroesophageal reflux disease associated with a history of erosive esophagitis
...

Associated Conditions: Erosive Esophagitis, GERD With Erosive Esophagitis, Gastro-esophageal Reflux Disease (GERD), Healing, Heartburn, Helicobacter Pylori Infection, Stress Ulcers, Zollinger-Ellison Syndrome, Conditions where a reduction of gastric acid secretion is required, Pathological hypersecretory conditions

Associated Therapies: -

Clinical Trials

Comparison of the Classical Healing Concept With the Complete Remission Concept After Treatment With Pantoprazole in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) (BY1023/M3-342)

Phase 4

Completed

Conditions: Gastroesophageal Reflux Disease

First Posted Date: 2006-05-15

Last Posted Date: 2012-05-07

Lead Sponsor: Takeda

Target Recruit Count: 639

Registration Number: NCT00325676

Locations: 🇿🇦
Altana Pharma/Nycomed, Somerset-West, South Africa

Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)

Phase 3

Completed

Conditions: Gastroesophageal Reflux Disease (GERD)

First Posted Date: 2006-04-11

Last Posted Date: 2012-05-07

Lead Sponsor: Takeda

Target Recruit Count: 2000

Registration Number: NCT00312806

Locations: 🇬🇧
Altana Pharma/Nycomed, Trowbridge, United Kingdom

Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea

Phase 4

Completed

Conditions: Acid Reflux Disease
Obstructive Sleep Apnea

First Posted Date: 2006-03-28

Last Posted Date: 2007-12-12

Lead Sponsor: University of Cincinnati

Target Recruit Count: 68

Registration Number: NCT00307944

Locations: 🇺🇸
University Ear, Nose and Throat Specialists, Cincinnati, Ohio, United States

Comparison of the Nighttime Effects of Two Different Drugs on Subjects With GERD

Phase 4

Completed

Conditions: Gastroesophageal Reflux Disease

First Posted Date: 2006-03-17

Last Posted Date: 2007-09-17

Lead Sponsor: VA Greater Los Angeles Healthcare System

Target Recruit Count: 23

Registration Number: NCT00304421

Locations: 🇺🇸
VA Greater Los Angeles Healthcare System, Los Angeles, California, United States

Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)

Phase 3

Completed

Conditions: Gastroesophageal Reflux Disease (GERD)
Peptic Ulcers

Interventions: Drug: Pantoprazole

First Posted Date: 2005-12-05

Last Posted Date: 2012-05-07

Lead Sponsor: Takeda

Target Recruit Count: 100

Registration Number: NCT00261300

Locations: 🇩🇪
Altana Pharma/Nycomed, Hannover, Germany

Determination of a Questionnaire After Treatment With Pantoprazole at Full Dose and Half Dose in Adult Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/UK-506)

Phase 4

Completed

Conditions: Gastroesophageal Reflux
GERD
GORD

First Posted Date: 2005-12-05

Last Posted Date: 2012-05-07

Lead Sponsor: Takeda

Target Recruit Count: 300

Registration Number: NCT00261339

Locations: 🇬🇧
Altana Pharma/Nycomed, Watford, United Kingdom

Comparison of a "Step-Up" Versus a "Step-Down" Treatment Strategy for Patients With New Onset Dyspepsia in General Practice (The DIAMOND-Study)

Not Applicable

Completed

Conditions: Dyspepsia
Gastrointestinal Diseases

Interventions: Drug: algeldrate/magnesium oxide
Drug: ranitidine
Drug: pantoprazole

First Posted Date: 2005-11-02

Last Posted Date: 2007-08-29

Lead Sponsor: Radboud University Medical Center

Target Recruit Count: 664

Registration Number: NCT00247715

Locations: 🇳🇱
Maastricht University, Maastricht, Limburg, Netherlands
🇳🇱
Radboud University Nijmegen Medical Center, Nijmegen, Gelderland, Netherlands
🇳🇱
UMC Utrecht, Utrecht, Netherlands

Determination of the Minimal Clinically Important Difference After Treatment With Pantoprazole in Patients With Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-340)

Phase 4

Completed

Conditions: Gastroesophageal Reflux

First Posted Date: 2005-11-01

Last Posted Date: 2012-05-07

Lead Sponsor: Takeda

Target Recruit Count: 600

Registration Number: NCT00246909

Locations: 🇺🇸
Altana Pharma/Nycomed, Milwaukee, Wisconsin, United States

Study of Intragastric pH Profile After 5 Days Pantoprazole 40 mg iv Followed by Oral Esomeprazole 40 mg po or Oral Pantoprazole 40 mg po

Phase 4

Completed

Conditions: Healthy

First Posted Date: 2005-09-21

Last Posted Date: 2011-01-21

Lead Sponsor: AstraZeneca

Target Recruit Count: 40

Registration Number: NCT00206050

Locations: 🇺🇸
Research Site, Oklahoma City, Oklahoma, United States

Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-339)

Phase 3

Completed

Conditions: Gastroesophageal Reflux

First Posted Date: 2005-09-14

Last Posted Date: 2012-05-07

Lead Sponsor: Takeda

Target Recruit Count: 1200

Registration Number: NCT00163306

Locations: 🇵🇱
Altana Pharma/Nycomed, Tychy, Poland

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