Tildrakizumab

Generic Name
Tildrakizumab
Brand Names
Ilumya, Ilumetri
Drug Type
Biotech
Chemical Formula
-
CAS Number
1326244-10-3
Unique Ingredient Identifier
DEW6X41BEK
Background

Tildrakizumab is a high-affinity, humanized, IgG1 κ antibody targeting interleukin 23 p19 that shows promise in the evolution of treatment strategy in chronic plaque psoriasis .
...

Indication

Moderate-severe plaque psoriasis , .

Associated Conditions
Moderate to Severe Plaque Psoriasis
Associated Therapies
-

A Study to Assess Patient-Reported Wellbeing Using Tildrakizumab in a Live Setting

Recruiting
Conditions
Interventions
First Posted Date
2024-07-05
Last Posted Date
2024-07-05
Lead Sponsor
Almirall, S.A.
Target Recruit Count
50
Registration Number
NCT06488170
Locations
🇨🇿

University Hospital Ostrava, Ostrava, Czechia

🇨🇿

Fakultní nemocnice Plzeň, with its registred seat at Edvarda Beneše, Pilsen, Czechia

🇨🇿

University Hospital in Motol, Praha, Czechia

and more 1 locations

A Study of Tildrakizumab in the Treatment of Genital Psoriasis (CZATCH-Genital-PsO)

Recruiting
Conditions
Interventions
First Posted Date
2023-09-08
Last Posted Date
2024-01-31
Lead Sponsor
Almirall, S.A.
Target Recruit Count
110
Registration Number
NCT06029257
Locations
🇦🇹

Medizinische Universität Graz, Graz, Styria, Austria

A Study to Assess the Effects of Switching From a Biologic Treatment to Tildrakizumab Using Patient-reported Outcomes in Adult Participants With Moderate to Severe Plaque Psoriasis

Recruiting
Conditions
Interventions
First Posted Date
2023-09-08
Last Posted Date
2024-01-31
Lead Sponsor
Almirall, S.A.
Target Recruit Count
50
Registration Number
NCT06030076
Locations
🇦🇹

Gesundheitszentrum Citypark Graz, Graz, Styria, Austria

Pilot Study Assessing the Effect of Tildrakizumab in Vitiligo

First Posted Date
2021-07-21
Last Posted Date
2024-11-12
Lead Sponsor
Premier Specialists, Australia
Target Recruit Count
12
Registration Number
NCT04971200
Locations
🇦🇺

Premier Specialists Pty Ltd, Sydney, New South Wales, Australia

Observational Real-world Evidence (RWE) Study to Assess Patient-reported Wellbeing Using Tildrakizumab in Live Setting - POSITIVE Study

Active, not recruiting
Conditions
Interventions
First Posted Date
2021-03-30
Last Posted Date
2024-07-30
Lead Sponsor
Almirall, S.A.
Target Recruit Count
782
Registration Number
NCT04823247
Locations
🇩🇪

Haut- und Laserzentrum Freising, Freising, Bavaria, Germany

Abiraterone Acetate in Combination With Tildrakizumab

First Posted Date
2020-07-07
Last Posted Date
2024-04-25
Lead Sponsor
Institute of Cancer Research, United Kingdom
Target Recruit Count
13
Registration Number
NCT04458311
Locations
🇬🇧

Belfast City Hospital, Belfast, UK, United Kingdom

🇬🇧

Cancer Research Centre at Weston Park Hospital, Sheffield, England, United Kingdom

🇬🇧

The Royal Marsden Hospital Foundation Trust, Sutton, UK, United Kingdom

and more 3 locations

Dose Reduction of IL17 and IL23 Inhibitors in Psoriasis

First Posted Date
2020-04-09
Last Posted Date
2024-01-19
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
244
Registration Number
NCT04340076
Locations
🇳🇱

Amphia Hospital, Breda, Netherlands

🇳🇱

Radboudumc, Nijmegen, Netherlands

🇳🇱

Máxima Medisch Centrum, Veldhoven, Netherlands

and more 16 locations

MIcrovascular dysfuNction In Moderate-severe Psoriasis

Phase 4
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-02-17
Last Posted Date
2024-08-07
Lead Sponsor
Marcelo F. Di Carli, MD, FACC
Target Recruit Count
36
Registration Number
NCT04271540
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Efficacy and Safety of Tildrakizumab in Participants With Moderate-to-Severe Chronic Plaque Psoriasis Who Are Non-Responders to Dimethyl Fumarate Therapy

First Posted Date
2020-02-11
Last Posted Date
2022-05-27
Lead Sponsor
Almirall, S.A.
Target Recruit Count
190
Registration Number
NCT04263610
Locations
🇩🇪

Investigator Site 3, Augsburg, Germany

🇬🇧

Investigator Site 2, London, United Kingdom

🇬🇧

Investigator Site 1, Bristol, United Kingdom

Observational Study of Tildrakizumab in Patients With Moderate to Severe Plaque Psoriasis in Routine Clinical Practice

Completed
Conditions
Interventions
First Posted Date
2019-12-18
Last Posted Date
2024-07-08
Lead Sponsor
Almirall, S.A.
Target Recruit Count
331
Registration Number
NCT04203693
Locations
🇳🇱

Investigational site 1, Breda, Netherlands

🇮🇹

Investigational site 5, Roma, Italy

🇩🇪

Investigational site 13, Berlin, Germany

and more 11 locations
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