MedPath

HE3286

Generic Name
HE3286
Drug Type
Small Molecule
Chemical Formula
C21H30O3
CAS Number
1001100-69-1
Unique Ingredient Identifier
PH8858757I
Indication

For the treatment of rheumatoid arthritis and type 2 diabetes.

NE3107 in Adults With Neurological Symptoms of Long COVID

Phase 2
Recruiting
Conditions
Long COVID
Interventions
Drug: Placebo
First Posted Date
2025-02-26
Last Posted Date
2025-05-13
Lead Sponsor
BioVie Inc.
Target Recruit Count
208
Registration Number
NCT06847191
Locations
🇺🇸

Clinical Trial Site, Farmington Hills, Michigan, United States

A Study of NE3107 in Early Parkinson's

Phase 2
Recruiting
Conditions
Parkinsons Disease (PD)
Interventions
Drug: Placebo
First Posted Date
2025-01-03
Last Posted Date
2025-04-23
Lead Sponsor
BioVie Inc.
Target Recruit Count
60
Registration Number
NCT06757010
Locations
🇺🇸

Invicro, New Haven, Connecticut, United States

🇺🇸

Northwestern Medicine, Chicago, Illinois, United States

🇺🇸

Quest Research Institute, Farmington Hills, Michigan, United States

and more 2 locations

Insulin-sensitizing NE3107 in Improving Sleep and Fatigue in Subjects With Traumatic Brain Injury

Phase 2
Recruiting
Conditions
Traumatic Brain Injury
Interventions
First Posted Date
2023-08-01
Last Posted Date
2024-07-17
Lead Sponsor
Neurological Associates of West Los Angeles
Target Recruit Count
5
Registration Number
NCT05970575
Locations
🇺🇸

The Regenesis Project, Santa Monica, California, United States

Insulin-Sensitizing Anti-Inflammatory Small Molecule for Investigative Treatment of Dementia

Phase 2
Completed
Conditions
Alzheimer Disease
Interventions
First Posted Date
2022-02-07
Last Posted Date
2024-07-09
Lead Sponsor
Neurological Associates of West Los Angeles
Target Recruit Count
23
Registration Number
NCT05227820
Locations
🇺🇸

Neurological Associates - The Interventional Group, Santa Monica, California, United States

NE3107 Activity and Safety in Patients With Parkinson's Disease Using Levodopa

Phase 1
Completed
Conditions
Parkinson Disease
Interventions
Drug: placebo
First Posted Date
2021-10-19
Last Posted Date
2023-02-08
Lead Sponsor
BioVie Inc.
Target Recruit Count
46
Registration Number
NCT05083260
Locations
🇺🇸

Parkinson's Disease & Movement Disorders Center Of Boca Raton, Boca Raton, Florida, United States

🇺🇸

Charter Research, Winter Park, Florida, United States

🇺🇸

University of Toledo, Toledo, Ohio, United States

and more 12 locations

A Phase 3 Study of NE3107 in Probable Alzheimer's Disease

Phase 3
Completed
Conditions
Alzheimer Disease
Interventions
Drug: Placebo
First Posted Date
2020-12-16
Last Posted Date
2023-11-21
Lead Sponsor
BioVie Inc.
Target Recruit Count
439
Registration Number
NCT04669028
Locations
🇺🇸

The Ohio State University, Columbus, Ohio, United States

A Study of the Safety, Tolerance and Assessment of HE3286 on Insulin Sensitivity and Hepatic Glucose Production

Phase 1
Completed
Conditions
Insulin Resistance
Interventions
First Posted Date
2009-10-07
Last Posted Date
2011-03-09
Lead Sponsor
Harbor Therapeutics
Target Recruit Count
5
Registration Number
NCT00991107
Locations
🇺🇸

Clinical Site, Baton Rouge, Louisiana, United States

Safety, Tolerance, Pharmacokinetics and Activity of HE3286 in Patients With Rheumatoid Arthritis

Phase 1
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2008-07-09
Last Posted Date
2011-06-14
Lead Sponsor
Harbor Therapeutics
Target Recruit Count
14
Registration Number
NCT00712114

Safety, Tolerance and Activity of HE3286 in Patients With Type 2 Diabetes Mellitus

Phase 2
Completed
Conditions
Type 2 Diabetes Mellitus
Interventions
Drug: Placebo
First Posted Date
2008-06-10
Last Posted Date
2011-06-14
Lead Sponsor
Harbor Therapeutics
Target Recruit Count
164
Registration Number
NCT00694057

Safety and Pharmacokinetics Study of HE3286 in Patients With Active, Mild-to-Moderate Ulcerative Colitis

Phase 1
Completed
Conditions
Ulcerative Colitis
Interventions
Drug: Placebo
First Posted Date
2008-03-05
Last Posted Date
2011-06-14
Lead Sponsor
Harbor Therapeutics
Target Recruit Count
27
Registration Number
NCT00628433
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