MedPath

Metenkefalin

Generic Name
Metenkefalin
Drug Type
Small Molecule
Chemical Formula
C27H35N5O7S
CAS Number
58569-55-4
Unique Ingredient Identifier
9JEZ9OD3AS
Background

Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.

Indication

Metenkefalin is indicated in Bosnia for the treatment of relapsing-remitting multiple sclerosis.

Clinical Trial to Evaluate the Efficacy and Safety of an Immunomodulatory Therapy for the Treatment of Patients With Moderate to Severe COVID-19 Infection

Phase 2
Completed
Conditions
COVID-19 Infection
Interventions
Drug: The standard of care
First Posted Date
2020-05-05
Last Posted Date
2020-12-24
Lead Sponsor
Bosnalijek D.D
Target Recruit Count
120
Registration Number
NCT04374032
Locations
🇧🇦

University Clinical Centre of the Republic of Srpska, Banja Luka, Bosnia and Herzegovina

🇧🇦

Cantonal Hospital Zenica, Zenica, Bosnia and Herzegovina

🇧🇦

Clinical Center University of Sarajevo, Sarajevo, Sarajevo Canton, Bosnia and Herzegovina

and more 2 locations

INNO-105 in Patients With Solid Tumors

Phase 1
Terminated
Conditions
Tumors
First Posted Date
2005-11-18
Last Posted Date
2007-05-14
Lead Sponsor
Innovive Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT00255333
Locations
🇺🇸

Mary Crowley Medical Research Center, Dallas, Texas, United States

🇺🇸

University of Maryland Greenebaum Cancer Center, Baltimore, Maryland, United States

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