MedPath

Pegenzileukin

Generic Name
Pegenzileukin
Drug Type
Biotech
CAS Number
2573074-47-0
Unique Ingredient Identifier
10WR240QN7

Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell Carcinoma

Phase 2
Withdrawn
Conditions
Oropharynx Cancer
Head and Neck Cancer
Squamous Cell Carcinoma
Interventions
First Posted Date
2022-09-10
Last Posted Date
2023-09-13
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT05535023
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

A Study of SAR444245 With or Without Other Anticancer Therapies for the Treatment of Adults and Adolescents With Relapsed or Refractory B Cell Lymphoma (Master Protocol) [Pegathor Lymphoma 205]

Phase 2
Active, not recruiting
Conditions
Classic Hodgkin Lymphoma
Diffuse Large B-cell Lymphoma
Interventions
First Posted Date
2022-01-05
Last Posted Date
2024-03-28
Lead Sponsor
Sanofi
Target Recruit Count
14
Registration Number
NCT05179603
Locations
🇨🇱

Investigational Site Number : 1520002, Santiago, Reg Metropolitana De Santiago, Chile

🇨🇱

Investigational Site Number : 1520004, Vina del Mar, Valparaíso, Chile

🇨🇱

Investigational Site Number : 1520001, Temuco, Chile

and more 5 locations

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

Phase 2
Terminated
Conditions
Oesophageal Squamous Cell Carcinoma
Colorectal Cancer
Oesophageal Adenocarcinoma
Gastric Cancer
Hepatocellular Carcinoma
Interventions
First Posted Date
2021-11-03
Last Posted Date
2024-10-02
Lead Sponsor
Sanofi
Target Recruit Count
138
Registration Number
NCT05104567
Locations
🇺🇸

Seattle Cancer Care Alliance Site Number : 8400009, Seattle, Washington, United States

🇳🇱

Investigational Site Number : 5280001, Amsterdam, Netherlands

🇮🇹

Investigational Site Number : 3800003, Milano, Italy

and more 26 locations

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)

Phase 2
Terminated
Conditions
Pleural Mesothelioma
Non-small Cell Lung Cancer
Interventions
First Posted Date
2021-06-07
Last Posted Date
2024-10-23
Lead Sponsor
Sanofi
Target Recruit Count
106
Registration Number
NCT04914897
Locations
🇮🇹

Investigational Site Number : 3800005, Aviano (PN), Friuli-Venezia Giulia, Italy

🇮🇹

Investigational Site Number : 3800001, Rozzano, Milano, Italy

🇰🇷

Investigational Site Number : 4100001, Seoul, Seoul-teukbyeolsi, Korea, Republic of

and more 32 locations

A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)

Phase 1
Terminated
Conditions
Malignant Melanoma
Squamous Cell Carcinoma of Skin
Interventions
First Posted Date
2021-06-04
Last Posted Date
2025-03-05
Lead Sponsor
Sanofi
Target Recruit Count
46
Registration Number
NCT04913220
Locations
🇫🇷

Investigational Site Number : 2500003, Bobigny, France

🇨🇱

Investigational Site Number : 1520006, Antofagasta, Chile

🇦🇺

Investigational Site Number : 0360001, Macquarie University, New South Wales, Australia

and more 21 locations

Isatuximab in Combination With Novel Agents in RRMM - Master Protocol

First Posted Date
2020-11-24
Last Posted Date
2025-03-14
Lead Sponsor
Sanofi
Target Recruit Count
197
Registration Number
NCT04643002
Locations
🇰🇷

Investigational Site Number : 4100002, Seoul, Korea, Republic of

🇺🇸

University of Illinois at Chicago- Site Number : 8400007, Chicago, Illinois, United States

🇺🇸

University of Michigan Health System - Ann Arbor- Site Number : 8400004, Ann Arbor, Michigan, United States

and more 23 locations

A Study Evaluating Safety and Therapeutic Activity of THOR-707 in Adult Subjects With Advanced or Metastatic Solid Tumors (THOR-707-101)

Phase 1
Active, not recruiting
Conditions
Metastasis
Interventions
Drug: Checkpoint inhibitor
First Posted Date
2019-07-05
Last Posted Date
2024-10-21
Lead Sponsor
Synthorx, Inc, a Sanofi company
Target Recruit Count
250
Registration Number
NCT04009681
Locations
🇦🇺

Investigational Site Number-2002, Victoria, Australia

🇦🇺

Investigational Site Number-2003, Victoria, Australia

🇨🇱

Investigational Site Number- 6001, Santiago, Chile

and more 21 locations
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