Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
Overview
Bupivacaine is a widely used local anesthetic agent.
Background
Bupivacaine is a widely used local anesthetic agent.
Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair. Bupivacaine, in liposome suspension, is indicated in patients aged 6 years and older for single-dose infiltration to produce postsurgical local analgesia. In adults, it is also indicated as an interscalene brachial plexus nerve block to produce postsurgical regional analgesia. Bupivacaine, in combination with meloxicam, is indicated for postsurgical analgesia in adult patients for up to 72 hours following foot and ankle, small-to-medium open abdominal, and lower extremity total joint arthroplasty surgical procedures. Bupivacaine, alone or in combination with epinephrine, is indicated in adults for the production of local or regional anesthesia or analgesia for surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and for obstetrical procedures. Specific concentrations and presentations are recommended for each type of block indicated to produce local or regional anesthesia or analgesia. Finally, its use is not indicated in all blocks given clinically significant risks associated with use.
Associated Conditions
- Acute Gouty Arthritis
- Adrenocortical Insufficiency
- Alopecia Areata (AA)
- Ankylosing Spondylitis (AS)
- Berylliosis
- Bullous dermatitis herpetiformis
- Congenital Adrenal Hyperplasia (CAH)
- Congenital Hypoplastic Anemia
- Dermatomyositis (DM)
- Discoid Lupus Erythematosus (DLE)
- Edema of the cerebrum
- Epicondylitis
- Hemolytic Anemia
- Hypercalcemia caused by Cancer
- Keloids Scars
- Leukemias
- Mycosis Fungoides (MF)
- Necrobiosis lipoidica diabeticorum
- Ocular Inflammation
- Ophthalmia, Sympathetic
- Osteoarthritis (OA)
- Pain, Labor
- Polymyositis
- Postoperative pain
- Psoriatic Arthritis
- Psoriatic plaque
- Pure Red Cell Aplasia
- Regional Enteritis
- Rheumatoid Arthritis
- Secondary thrombocytopenia
- Stevens-Johnson Syndrome
- Synovitis
- Systemic Lupus Erythematosus
- Temporal Arteritis
- Trichinosis
- Tuberculous Meningitis
- Ulcerative Colitis
- Uveitis
- Acute Bursitis
- Acute Idiopathic Nephrotic Syndrome
- Acute Lupus Erythematosus
- Acute Multiple sclerosis
- Acute Rheumatic heart disease, unspecified
- Acute nonspecific tenosynovitis
- Cystic tumors of aponeurosis
- Cystic tumors of tendon
- Disseminated Pulmonary Tuberculosis (TB)
- Exfoliative erythroderma
- Inflammatory lesions of granuloma annulare
- Inflammatory lesions of lichen planus
- Inflammatory lesions of lichen simplex
- Non-suppurative Thyroiditis
- Permphigus
- Severe Allergic Reactions
Clinical Trials
FDA Approved Products
Singapore Approved Products
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